Caprico Biotechnologies


Fluorescently labelled antibodies for flow cytometry in research and clinical applications


CapricoBio produces high-quality fluorescent labelled antibodies for cellular immunophenotyping in clinical diagnosis, research applications, immunotherapy monitoring and clinical trials.

 

Immunophenotyping in diagnostic and basic research applications:

Caprico Biotechnologies' produces fluorescent labelled antibodies specific for human immune cells, which can be used in both research and diagnostic applications. All antibodies are highly purified and conjugated with different fluorochromes such as Fluorescein isothiocyanate (FITC), Phycoerythrin (PE), Peridinin-chlorophyll-protein complex (PerCP), Allophycocyanin (APC), and more.

 

Immunophenotyping in Immunotherapy and Clinical Trials:

Caprico Biotechnologies is developing a number of Immunophenotyping kits to help evaluate the efficacy of immunotherapy in cancer (e.g., CD3, CD117, CD71 and CD25 expressing cells) and a ready to use cocktail of antibodies to quantify the number of CD4+ T cells per ml of blood after HAART therapy in the tretment of HIV.

 

Also in development are specific immunophenotyping kits for T cell, B cell, and antigen presenting cells (APCs) to allow determination of the effects of a new drug or a treatment strategy on a patients' immune system.

 

More inormation on these kits wil be available in the coming months.

 



Anti-p53 (Clones PAb1620 and PAb122)

 

p53 acts as a tumor suppressor in many tumor types; depending on the physiological circumstances and cell type it induces growth arrest or apoptosis. Involved in cell cycle regulation as a trans-activator, p53 acts to negatively regulate cell division by controlling a set of genes required for this process. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.

 

p53 localizes in the nucleus, yet can be chaperoned to the cytoplasm by the negative regulator, MDM2. p53 fluctuates between latent and active DNA-binding conformations and is differentially activated through post-translational modifications, including phosphorylation and acetylation.

 

Our p53 antibodies for flow cytometry.

 

Anti p53 Clone PAb122 binds to amino acids 371 - 378 of p53 and is recommended for the detection of a conserved denaturation-resistant determinant of the p53 protein.

 

Anti p53 Clone PAb1620 binds a conformational epitope that disappears in some mutant p53 or upon denaturation. It therefore preferentially immunoprecipitates wild-type p53 and does not cause immunoprecipitation of mutant and denatured p53.

 

Caprico Biotechnologies' antibodies are specific for human immune cells, and can be used in both research and diagnostic applications.

 



Flow Cytometry Antibodies - 3 for 2 Offer!

 

CapricoBio's high-quality fluorescent labelled antibodies for flow cytometry are now 3 for 2!

 

Pick any 3 antibodies in the CapricoBio range and only pay for 2 of them. Naturally it is the cheapest one that's free, but if you buy 6, 9, 12 or more antibodies, we'll be sure to organise them in sets of 3 to maximise your discount.

 

Just quote CBW416 on your order to get the offer.

 

Caprico Biotechnologies' antibodies are specific for human immune cells, and can be used in both research and diagnostic applications.

 

Caprico antibodies

Every antibody is highly purified and conjugated with different fluorochromes such as Fluorescein isothiocyanate (FITC), Phycoerythrin (PE), Peridinin-chlorophyll-protein complex (PerCP), Allophycocyanin (APC), and more.

 

Offer valid throughout 2017* Terms and conditions apply, but we want to give you the discount so please contact us if you have any questions at all.

 

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