Parkinson’s disease (PD) is a neurological disorder in which the main pathophysiology is the progressive degeneration of dopaminergic neurones in the substantia nigra. Parkinson’s disease (PD) is characterised by the accumulation of misfolded and aggregated α-synuclein (α-syn/SNCA) into intraneuronal inclusions called Lewy bodies, but it is not clear whether Lewy bodies play a role in nerve cell death or if they are simply part of the cellular response. The major component in Lewy bodies is α-synuclein, however lewy bodies have been shown to contain many different proteins. Changes in non-dopaminergic neural substrates such as serotonin, noradrenaline and acetylcholine also contribute to the motor and non-motor symptoms of Parkinson's Disease.
Newmarket Scientific provides antibodies to a large number of Parkinson’s disease associated proteins and molecules and we continually monitor the latest publications in this area with the aim of identifying new and emerging potential targets to develop antibodies to, allowing us to better serve those at the forefront of Parkinson’s disease research.
Below is the list of Parkinson’s disease targets we cover with our antibodies along with links to more detailed information. If you are looking for an antibody to a specific target that isnt listed, please email us as it is likely that either we have it in production or if not we will be happy to add it to our antibody development list?
Adenosine receptor A2a (ADORA2A) antibodies
NS Reagents |
AB18-10067 |
N-terminal peptide |
Hu|Ms|Rt |
WB |
Affinity |
DF4850 |
Internal region |
Hu|Ms|Rt |
WB|IHC|IF|E |
Affinity |
DF4906 |
Internal region |
Hu|Ms |
WB|IHC|IF|E |
Affinity
|
DF6482 |
Internal region |
Hu|Ms|Rt |
WB|IHC|IF|E |
Alpha-synuclein (SNCA) Antibodies and ELISA kit
Biosensis |
C-1795-50 |
aa 61-95 |
Hu|Ms|Rt |
WB|IHC|ICC |
Biosensis |
M-1402-100 |
Full length |
Hu|Ms|Rt |
WB|ICC |
Biosensis |
R-075-100 |
C-terminal |
Hu|Ms|Rt |
WB|IHC |
Agrisera |
AS08 358 |
aa 1-15 |
Hu|Primate |
WB|IHC|E |
Agrisera |
AS13 2717 |
aa 131-140 oligomer specific |
Hu|Ms |
IHC|E|Dot |
Agrisera |
AS13 2718 |
aa 111-125 oligomer specific |
Hu|Ms |
IHC|E|Dot
|
Agrisera |
AS13 2719 |
N-terminal peptide |
Hu|Ms |
IHC|E|Dot |
Affinity |
AF0402 |
C-terminal |
Hu|Ms|Rt |
WB|E |
Affinity |
AF6285 |
C-terminal |
Hu|Ms|Rt |
WB|IHC|E |
Affinity |
AF6286 |
C-terminal |
Hu|Ms|Rt |
WB|E |
Affinity |
BF0582 |
Prtn fragment |
Hu|Ms|Rt |
WB|IHC|E |
Affinity (Ser129) |
AF3285 |
Phosphopeptide |
Hu|Ms|Rt |
WB|IHC|E |
Affinity (Tyr133) |
AF3286 |
Phosphopeptide |
Hu|Ms|Rt |
WB|E |
Affinity (Tyr136) |
AF3287 |
Phosphopeptide |
Hu|Ms|Rt |
WB|IHC|E |
Biosensis |
BEK-2216 |
ELISA Kit |
Hu
|
E
|
Ataxin-2 (ATXN2) antibodies
Affinity
|
DF3799 |
Central region
|
Hu |
WB|IF|E |
Beta-synuclein antibodies
Biosensis |
R-056-100 |
aa 108-125 |
Hu|Rt |
WB|IHC |
Biosensis |
R-1683-500 |
aa 99-113 |
Hu|Ms |
WB|IHC |
Biosensis |
S-077-100 |
aa 108-125 |
Hu|Ms|Rt |
IHC |
Affinity
|
AF5324 |
C-terminal |
Hu|Ms|Rt |
WB|IHC|IF|E |
CDK5 (Cyclin-dependent-like kinase 5) Antibodies
NS Reagents |
AB20-10126 |
N-terminal |
Hu|Ms|Rt|Mk |
WB|IHC|IF |
Affinity |
AF6371 |
N-terminal |
Hu|Ms|Rt|Mk |
WB|IHC|IF|E |
Affinity |
BF0121 |
Prtn fragment |
Hu|Ms|Rt|Mk |
WB|IHC|IF|E |
Affinity (Tyr15) |
AF3371 |
Phosphopeptide |
Hu|Ms|Rt|Mk |
WB|IF |
Affinity (Ser159) |
AF8366 |
Phosphopeptide |
Hu|Rt|Mk |
WB|IHC|IF|E|FC |
DJ1 (PARK7) Antibodies
NS Reagents |
AB18-10077 |
Full length |
Hu|Ms|Rt |
WB|IF |
Biosensis |
M-1573-100 |
Full length |
Hu |
WB|ICC |
Biosensis |
R-1682-500 |
Peptide aa 2-16 |
Hu|Ms |
WB|IHC |
Affinity |
AF0380 |
C-terminal |
Hu|Ms|Rt |
WB|IF/ICC|E |
Affinity |
DF6169 |
C-terminal |
Hu|Ms|Rt |
WB|IHC|IF/ICC|E |
EIF4A3 Antibodies
NS Reagents |
AB19-10116 |
Full length
|
Hu|Ms|Rt |
WB|IHC |
Affinity |
DF12071 |
Internal region |
Hu|Ms|Rt |
WB|IHC|IF/ICC|E |
EIF4G1 Antibodies
NS Reagents |
AB19-10117 |
Peptide |
Hu |
WB|IHC |
Affinity |
AF7849 |
Internal region |
Hu|Ms|Rt |
WB|E |
Affinity |
AF7850 |
Internal region |
Hu|Ms|Rt |
WB|E |
Affinity |
DF7614 |
Internal region |
Hu |
WB|E |
Affinity |
DF7764 |
Internal region |
Hu |
WB|E |
Affinity (Ser1147) |
AF2341 |
Phosphopeptide
|
Hu|Ms|Rt |
WB|IHC |
Affinity (Ser1147) |
AF7349 |
Phosphopeptide |
Hu|Ms|Rt |
WB|E |
Affinity (Ser1185) |
AF7350 |
Phosphopeptide |
Hu|Ms|Rt |
WB|IHC|E |
F-box only protein 7 (FBXO7) Antibodies
NS Reagents |
AB19-10119 |
C-terminal
|
Hu|Ms|Rt |
WB|IHC|IF |
Affinity |
DF13008 |
C-terminal
|
Hu|Ms|Rt |
WB |
Beta-glucocerebrosidase (GBA) Antibodies
NS Reagents |
AB19-10120 |
Full length
|
Hu|Ms|Rt |
WB|IHC |
Affinity |
DF8237 |
Central region |
Hu|Ms |
WE|E |
Gamma-synuclein Antibodies
Biosensis |
R-058-100 |
aa 114-127 |
Hu|Rt |
WB|IHC |
Biosensis |
S-069-20 |
aa 114-127 |
Hu|Rt |
WB|IHC |
Affinity |
AF0258 |
C-terminal
|
Hu|Ms|Rt |
WB|IHC|IF/ICC|E |
Affinity |
DF6985 |
C-terminal
|
Hu|Ms|Rt |
WB|IHC|IF/ICC|E |
GTP cyclohydrolase 1 (GCH1) Antibodies
NS Reagents |
AB19-10111 |
Peptide |
Hu |
WB|IHC |
Affinity |
DF9546 |
Central region |
Hu|Ms|Rt |
WB|E |
Histone deacetylase 6 (HDAC6) Antibodies
NS Reagents |
AB19-10114 |
Full length |
Hu|Ms |
IHC|IF |
Affinity |
AF0594 |
N-terminal
|
Hu|Ms |
WB|IHC|IF/ICC|E |
Affinity |
AF5359 |
C-terminal
|
Hu|Ms |
WB|IHC|E |
Affinity |
DF6582 |
N-terminal
|
Hu|Ms|Rt |
WB|IHC|IF/ICC|E |
Affinity (Ser22)
|
AF3485 |
Phosphopeptide |
Hu|Ms |
WB|IHC|IF/ICC|E |
HtrA Serine Peptidase 2 (HTRA2) Antibodies
NS Reagents |
AB19-10118 |
C-terminal peptide |
Hu|Ms|RT |
WB|IHC |
Affinity |
DF7626 |
peptide-central region |
Hu |
WB|E |
Affinity (Ser212)
|
AF8275 |
Phosphopeptide |
Hu|Ms|Rt |
WB|E |
Affinity (Ser142)
|
AF8381 |
Phosphopeptide |
Hu|Ms|Rt |
WB|E |
Leucine-Rich Repeat Kinase 2 (LRRK2) Antibodies
Biosensis |
R-183-50 |
aa 946-962 |
Hu |
IHC |
Affinity |
DF2668 |
C-terminal
|
Hu|Ms |
WB|E |
Biosensis |
PE-1608 |
|
|
small molecule LRKK2 inhibitor |
Nociceptin opioid peptide receptor (OPRL1) Antibodies
NS Reagents |
AB18-10069 |
N-terminal
|
Hu|Ms|Rt |
WB |
Affinity |
DF2834 |
C-terminal
|
Hu|Ms|Rt |
WB |
Parkin RBR E3 Ubiquitin Protein Ligase (PRKN/Parkin) Antibodies
Biosensis |
R-113-100 |
aa 305-323 |
Hu|Rt |
WB|IHC|E |
Biosensis |
R-114-100
|
aa 295-311
|
Hu|Rt |
WB|IHC|E |
Biosensis |
PE-1253 (control)
|
aa 305-323 |
- |
IHC |
Affinity |
AF0235 |
Peptide |
Hu|Ms|Rt |
WB|IHC|E |
PTEN induced kinase 1 (PINK1) Antibodies
Affinity |
AF4791 |
Central region |
Hu|Ms |
WB|E |
Affinity |
AF7581 |
Central region |
Hu|Ms|Rt |
WB|E |
Affinity |
DF7742 |
C-terminal
|
Hu|Ms|Rt |
WB|IHC|E |
Affinity (Thr313)
|
AF4491 |
Phosphopeptide |
Hu|Ms |
WB|E |
Affinity (Ser228)
|
AF7081 |
Phosphopeptide |
Hu|Ms|Rt |
WB|IHC|E |
Ubiquitin Cterminal Hydroxylase 1 (UCHL1/PGP9.5) Antibodies
NS Reagents |
AA17-10045 |
Full length
|
Hu|Ms |
WB |
Biosensis |
C-1406-50 |
Full length |
Hu|Rt|Ms |
WB|ICC |
Biosensis |
M-1407-100 |
Full length |
Hu|Rt|Ms |
WB|ICC|IHC |
Biosensis |
M-1407-100 |
Full length |
Hu|Rt|Ms |
WB|ICC |
Affinity |
AF0243 |
C-terminal
|
Hu|Rt|Ms |
WB|ICC/IF|IHC|E |
Affinity |
DF6854 |
C-terminal
|
Hu|Rt|Ms |
WB|ICC/IF|IHC|E |
Vesicle-associated membrane protein-associated protein B (VAPB) Antibodies
NS Reagents |
AB19-10107 |
Full length |
Hu|Ms |
WB|IHC|IF |
Affinity |
DF7303 |
C-terminal
|
Hu|Ms|Rt |
WB|IHC|E |
Vacuolar protein sorting 35 (VPS35) Antibodies
NS Reagents |
AB19-10109 |
peptide |
Hu|Ms |
WB|IHC |
NS Reagents |
AB19-10110 |
N-terminal
|
Hu|Ms|Rt |
WB |
Affinity |
DF12793 |
Internal region |
Hu|Ms|Rt |
WB |
If you are looking for an antibody to a specific target that isn.t listed, please email us as very likely it is in development OR we can always add it to our development list.
Why not work with us on the development of your antibody? We cover ther cost, you do the testing!
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