Newmarket Scientific
Newmarket Scientific








NEWS: Antibodies for Parkinson’s Disease Research



Parkinson’s disease (PD) is a neurological disorder in which the main pathophysiology is the progressive degeneration of dopaminergic neurones in the substantia nigra. Parkinson’s disease (PD) is characterised by the accumulation of misfolded and aggregated α-synuclein (α-syn/SNCA) into intraneuronal inclusions called Lewy bodies, but it is not clear whether Lewy bodies play a role in nerve cell death or if they are simply part of the cellular response. The major component in Lewy bodies is α-synuclein, however lewy bodies have been shown to contain many different proteins. Changes in non-dopaminergic neural substrates such as serotonin, noradrenaline and acetylcholine also contribute to the motor and non-motor symptoms of Parkinson's Disease.

 

Newmarket Scientific provides antibodies to a large number of Parkinson’s disease associated proteins and molecules and we continually monitor the latest publications in this area with the aim of identifying new and emerging potential targets to develop antibodies to, allowing us to better serve those at the forefront of Parkinson’s disease research.

 

Below is the list of Parkinson’s disease targets we cover with our antibodies along with links to more detailed information. If you are looking for an antibody to a specific target that isnt listed, please email us as it is likely that either we have it in production or if not we will be happy to add it to our antibody development list?

 

 

Adenosine receptor A2a (ADORA2A) antibodies

NS Reagents AB18-10067 N-terminal peptide Hu|Ms|Rt WB
Affinity DF4850 Internal region Hu|Ms|Rt WB|IHC|IF|E
Affinity DF4906 Internal region Hu|Ms WB|IHC|IF|E
Affinity
DF6482 Internal region Hu|Ms|Rt WB|IHC|IF|E

 

Alpha-synuclein (SNCA) Antibodies and ELISA kit

Biosensis C-1795-50 aa 61-95 Hu|Ms|Rt WB|IHC|ICC
Biosensis M-1402-100 Full length Hu|Ms|Rt WB|ICC
Biosensis R-075-100 C-terminal Hu|Ms|Rt WB|IHC
Agrisera AS08 358 aa 1-15 Hu|Primate WB|IHC|E
Agrisera AS13 2717 aa 131-140
oligomer specific
Hu|Ms IHC|E|Dot
Agrisera AS13 2718 aa 111-125
oligomer specific
Hu|Ms IHC|E|Dot
Agrisera AS13 2719 N-terminal peptide Hu|Ms IHC|E|Dot
Affinity AF0402 C-terminal Hu|Ms|Rt WB|E
Affinity AF6285 C-terminal Hu|Ms|Rt WB|IHC|E
Affinity AF6286 C-terminal Hu|Ms|Rt WB|E
Affinity BF0582 Prtn fragment Hu|Ms|Rt WB|IHC|E
Affinity (Ser129) AF3285 Phosphopeptide Hu|Ms|Rt WB|IHC|E
Affinity (Tyr133) AF3286 Phosphopeptide Hu|Ms|Rt WB|E
Affinity (Tyr136) AF3287 Phosphopeptide Hu|Ms|Rt WB|IHC|E
Biosensis BEK-2216 ELISA Kit Hu
E

 

Ataxin-2 (ATXN2) antibodies

Affinity
DF3799 Central region
Hu WB|IF|E

 

Beta-synuclein antibodies

Biosensis R-056-100 aa 108-125 Hu|Rt WB|IHC
Biosensis R-1683-500 aa 99-113 Hu|Ms WB|IHC
Biosensis S-077-100 aa 108-125 Hu|Ms|Rt IHC
Affinity
AF5324 C-terminal Hu|Ms|Rt WB|IHC|IF|E

 

CDK5 (Cyclin-dependent-like kinase 5) Antibodies

NS Reagents AB20-10126 N-terminal Hu|Ms|Rt|Mk WB|IHC|IF
Affinity AF6371 N-terminal Hu|Ms|Rt|Mk WB|IHC|IF|E
Affinity BF0121 Prtn fragment Hu|Ms|Rt|Mk WB|IHC|IF|E
Affinity (Tyr15) AF3371 Phosphopeptide Hu|Ms|Rt|Mk WB|IF
Affinity (Ser159) AF8366 Phosphopeptide Hu|Rt|Mk WB|IHC|IF|E|FC

 

DJ1 (PARK7) Antibodies

NS Reagents AB18-10077 Full length  Hu|Ms|Rt WB|IF
Biosensis M-1573-100 Full length Hu WB|ICC
Biosensis R-1682-500 Peptide aa 2-16 Hu|Ms WB|IHC
Affinity AF0380 C-terminal  Hu|Ms|Rt WB|IF/ICC|E
Affinity DF6169 C-terminal  Hu|Ms|Rt WB|IHC|IF/ICC|E

 

EIF4A3 Antibodies

NS Reagents AB19-10116 Full length
Hu|Ms|Rt WB|IHC
Affinity DF12071 Internal region Hu|Ms|Rt WB|IHC|IF/ICC|E

 

EIF4G1 Antibodies

NS Reagents AB19-10117 Peptide Hu WB|IHC
Affinity AF7849 Internal region Hu|Ms|Rt WB|E
Affinity AF7850 Internal region Hu|Ms|Rt WB|E
Affinity DF7614 Internal region Hu WB|E
Affinity DF7764 Internal region Hu WB|E
Affinity (Ser1147) AF2341 Phosphopeptide
Hu|Ms|Rt WB|IHC
Affinity (Ser1147) AF7349 Phosphopeptide Hu|Ms|Rt WB|E
Affinity (Ser1185) AF7350 Phosphopeptide Hu|Ms|Rt WB|IHC|E

 

F-box only protein 7 (FBXO7) Antibodies

NS Reagents AB19-10119 C-terminal
Hu|Ms|Rt WB|IHC|IF
Affinity DF13008 C-terminal
Hu|Ms|Rt WB

 

Beta-glucocerebrosidase (GBA) Antibodies

NS Reagents AB19-10120 Full length
Hu|Ms|Rt WB|IHC
Affinity DF8237 Central region Hu|Ms WE|E

 

Gamma-synuclein Antibodies

Biosensis R-058-100 aa 114-127 Hu|Rt WB|IHC
Biosensis S-069-20 aa 114-127 Hu|Rt WB|IHC
Affinity AF0258 C-terminal
Hu|Ms|Rt WB|IHC|IF/ICC|E
Affinity DF6985 C-terminal
Hu|Ms|Rt WB|IHC|IF/ICC|E

 

GTP cyclohydrolase 1 (GCH1) Antibodies

NS Reagents AB19-10111 Peptide Hu WB|IHC
Affinity DF9546 Central region Hu|Ms|Rt WB|E

 

Histone deacetylase 6 (HDAC6) Antibodies

NS Reagents AB19-10114 Full length Hu|Ms IHC|IF
Affinity AF0594 N-terminal
Hu|Ms WB|IHC|IF/ICC|E
Affinity AF5359 C-terminal
Hu|Ms WB|IHC|E
Affinity DF6582 N-terminal
Hu|Ms|Rt WB|IHC|IF/ICC|E
Affinity (Ser22)
AF3485 Phosphopeptide Hu|Ms WB|IHC|IF/ICC|E

 

HtrA Serine Peptidase 2 (HTRA2) Antibodies

NS Reagents AB19-10118 C-terminal peptide Hu|Ms|RT WB|IHC
Affinity DF7626 peptide-central region Hu WB|E
Affinity (Ser212)
AF8275 Phosphopeptide Hu|Ms|Rt WB|E
Affinity (Ser142)
AF8381 Phosphopeptide Hu|Ms|Rt WB|E

 

Leucine-Rich Repeat Kinase 2 (LRRK2) Antibodies

Biosensis R-183-50 aa 946-962 Hu IHC
Affinity DF2668 C-terminal
Hu|Ms WB|E
Biosensis PE-1608     small molecule LRKK2 inhibitor

 

Nociceptin opioid peptide receptor (OPRL1) Antibodies

NS Reagents AB18-10069 N-terminal
Hu|Ms|Rt WB
Affinity DF2834 C-terminal
Hu|Ms|Rt WB

 

Parkin RBR E3 Ubiquitin Protein Ligase (PRKN/Parkin) Antibodies

Biosensis R-113-100 aa 305-323 Hu|Rt WB|IHC|E
Biosensis R-114-100
aa 295-311
Hu|Rt WB|IHC|E
Biosensis PE-1253 (control)
aa 305-323  - IHC
Affinity AF0235 Peptide Hu|Ms|Rt WB|IHC|E



PTEN induced kinase 1 (PINK1) Antibodies

Affinity AF4791 Central region Hu|Ms WB|E
Affinity AF7581 Central region Hu|Ms|Rt WB|E
Affinity DF7742 C-terminal
Hu|Ms|Rt WB|IHC|E
Affinity (Thr313)
AF4491 Phosphopeptide Hu|Ms WB|E
Affinity (Ser228)
AF7081 Phosphopeptide Hu|Ms|Rt WB|IHC|E

 

Ubiquitin Cterminal Hydroxylase 1 (UCHL1/PGP9.5) Antibodies

NS Reagents AA17-10045 Full length
Hu|Ms WB
Biosensis C-1406-50 Full length Hu|Rt|Ms WB|ICC
Biosensis M-1407-100 Full length Hu|Rt|Ms WB|ICC|IHC
Biosensis M-1407-100 Full length Hu|Rt|Ms WB|ICC
Affinity AF0243 C-terminal
Hu|Rt|Ms WB|ICC/IF|IHC|E
Affinity DF6854 C-terminal
Hu|Rt|Ms WB|ICC/IF|IHC|E

 

Vesicle-associated membrane protein-associated protein B (VAPB) Antibodies

NS Reagents AB19-10107 Full length Hu|Ms WB|IHC|IF
Affinity DF7303 C-terminal
Hu|Ms|Rt WB|IHC|E

 

Vacuolar protein sorting 35 (VPS35) Antibodies

NS Reagents AB19-10109 peptide Hu|Ms WB|IHC
NS Reagents AB19-10110 N-terminal
Hu|Ms|Rt WB
Affinity DF12793 Internal region Hu|Ms|Rt WB

 

If you are looking for an antibody to a specific target that isn.t listed, please email us as very likely it is in development OR we can always add it to our development list.

 

Why not work with us on the development of your antibody? We cover ther cost, you do the testing!

 



Looking for an antibody not listed? Let us know.