NEWS: Antibodies for Parkinson’s Disease Research

Parkinson’s disease (PD) is a neurological disorder in which the main pathophysiology is the progressive degeneration of dopaminergic neurones in the substantia nigra. Parkinson’s disease (PD) is characterised by the accumulation of misfolded and aggregated α-synuclein (α-syn/SNCA) into intraneuronal inclusions called Lewy bodies, but it is not clear whether Lewy bodies play a role in nerve cell death or if they are simply part of the cellular response. The major component in Lewy bodies is α-synuclein, however lewy bodies have been shown to contain many different proteins. Changes in non-dopaminergic neural substrates such as serotonin, noradrenaline and acetylcholine also contribute to the motor and non-motor symptoms of Parkinson's Disease.

Newmarket Scientific provides antibodies to a large number of Parkinson’s disease associated proteins and molecules and we continually monitor the latest publications in this area with the aim of identifying new and emerging potential targets to develop antibodies to, allowing us to better serve those at the forefront of Parkinson’s disease research.

Below is the list of Parkinson’s disease targets we cover with our antibodies along with links to more detailed information. If you are looking for an antibody to a specific target that isnt listed, please email us as it is likely that either we have it in production or if not we will be happy to add it to our antibody development list?

Adenosine receptor A2a (ADORA2A) antibodies

NS Reagents	AB18-10067	N-terminal peptide	Hu\|Ms\|Rt	WB
Affinity	DF4850	Internal region	Hu\|Ms\|Rt	WB\|IHC\|IF\|E
Affinity	DF4906	Internal region	Hu\|Ms	WB\|IHC\|IF\|E
Affinity	DF6482	Internal region	Hu\|Ms\|Rt	WB\|IHC\|IF\|E

Alpha-synuclein (SNCA) Antibodies and ELISA kit

Biosensis	C-1795-50	aa 61-95	Hu\|Ms\|Rt	WB\|IHC\|ICC
Biosensis	M-1402-100	Full length	Hu\|Ms\|Rt	WB\|ICC
Biosensis	R-075-100	C-terminal	Hu\|Ms\|Rt	WB\|IHC
Agrisera	AS08 358	aa 1-15	Hu\|Primate	WB\|IHC\|E
Agrisera	AS13 2717	aa 131-140 oligomer specific	Hu\|Ms	IHC\|E\|Dot
Agrisera	AS13 2718	aa 111-125 oligomer specific	Hu\|Ms	IHC\|E\|Dot
Agrisera	AS13 2719	N-terminal peptide	Hu\|Ms	IHC\|E\|Dot
Affinity	AF0402	C-terminal	Hu\|Ms\|Rt	WB\|E
Affinity	AF6285	C-terminal	Hu\|Ms\|Rt	WB\|IHC\|E
Affinity	AF6286	C-terminal	Hu\|Ms\|Rt	WB\|E
Affinity	BF0582	Prtn fragment	Hu\|Ms\|Rt	WB\|IHC\|E
Affinity (Ser129)	AF3285	Phosphopeptide	Hu\|Ms\|Rt	WB\|IHC\|E
Affinity (Tyr133)	AF3286	Phosphopeptide	Hu\|Ms\|Rt	WB\|E
Affinity (Tyr136)	AF3287	Phosphopeptide	Hu\|Ms\|Rt	WB\|IHC\|E
Biosensis	BEK-2216	ELISA Kit	Hu	E

Ataxin-2 (ATXN2) antibodies

Affinity

DF3799

Central region

WB|IF|E

Beta-synuclein antibodies

Biosensis	R-056-100	aa 108-125	Hu\|Rt	WB\|IHC
Biosensis	R-1683-500	aa 99-113	Hu\|Ms	WB\|IHC
Biosensis	S-077-100	aa 108-125	Hu\|Ms\|Rt	IHC
Affinity	AF5324	C-terminal	Hu\|Ms\|Rt	WB\|IHC\|IF\|E

CDK5 (Cyclin-dependent-like kinase 5) Antibodies

NS Reagents	AB20-10126	N-terminal	Hu\|Ms\|Rt\|Mk	WB\|IHC\|IF
Affinity	AF6371	N-terminal	Hu\|Ms\|Rt\|Mk	WB\|IHC\|IF\|E
Affinity	BF0121	Prtn fragment	Hu\|Ms\|Rt\|Mk	WB\|IHC\|IF\|E
Affinity (Tyr15)	AF3371	Phosphopeptide	Hu\|Ms\|Rt\|Mk	WB\|IF
Affinity (Ser159)	AF8366	Phosphopeptide	Hu\|Rt\|Mk	WB\|IHC\|IF\|E\|FC

DJ1 (PARK7) Antibodies

NS Reagents	AB18-10077	Full length	Hu\|Ms\|Rt	WB\|IF
Biosensis	M-1573-100	Full length	Hu	WB\|ICC
Biosensis	R-1682-500	Peptide aa 2-16	Hu\|Ms	WB\|IHC
Affinity	AF0380	C-terminal	Hu\|Ms\|Rt	WB\|IF/ICC\|E
Affinity	DF6169	C-terminal	Hu\|Ms\|Rt	WB\|IHC\|IF/ICC\|E

EIF4A3 Antibodies

NS Reagents	AB19-10116	Full length	Hu\|Ms\|Rt	WB\|IHC
Affinity	DF12071	Internal region	Hu\|Ms\|Rt	WB\|IHC\|IF/ICC\|E

EIF4G1 Antibodies

NS Reagents	AB19-10117	Peptide	Hu	WB\|IHC
Affinity	AF7849	Internal region	Hu\|Ms\|Rt	WB\|E
Affinity	AF7850	Internal region	Hu\|Ms\|Rt	WB\|E
Affinity	DF7614	Internal region	Hu	WB\|E
Affinity	DF7764	Internal region	Hu	WB\|E
Affinity (Ser1147)	AF2341	Phosphopeptide	Hu\|Ms\|Rt	WB\|IHC
Affinity (Ser1147)	AF7349	Phosphopeptide	Hu\|Ms\|Rt	WB\|E
Affinity (Ser1185)	AF7350	Phosphopeptide	Hu\|Ms\|Rt	WB\|IHC\|E

F-box only protein 7 (FBXO7) Antibodies

NS Reagents	AB19-10119	C-terminal	Hu\|Ms\|Rt	WB\|IHC\|IF
Affinity	DF13008	C-terminal	Hu\|Ms\|Rt	WB

Beta-glucocerebrosidase (GBA) Antibodies

NS Reagents	AB19-10120	Full length	Hu\|Ms\|Rt	WB\|IHC
Affinity	DF8237	Central region	Hu\|Ms	WE\|E

Gamma-synuclein Antibodies

Biosensis	R-058-100	aa 114-127	Hu\|Rt	WB\|IHC
Biosensis	S-069-20	aa 114-127	Hu\|Rt	WB\|IHC
Affinity	AF0258	C-terminal	Hu\|Ms\|Rt	WB\|IHC\|IF/ICC\|E
Affinity	DF6985	C-terminal	Hu\|Ms\|Rt	WB\|IHC\|IF/ICC\|E

GTP cyclohydrolase 1 (GCH1) Antibodies

NS Reagents	AB19-10111	Peptide	Hu	WB\|IHC
Affinity	DF9546	Central region	Hu\|Ms\|Rt	WB\|E

Histone deacetylase 6 (HDAC6) Antibodies

NS Reagents	AB19-10114	Full length	Hu\|Ms	IHC\|IF
Affinity	AF0594	N-terminal	Hu\|Ms	WB\|IHC\|IF/ICC\|E
Affinity	AF5359	C-terminal	Hu\|Ms	WB\|IHC\|E
Affinity	DF6582	N-terminal	Hu\|Ms\|Rt	WB\|IHC\|IF/ICC\|E
Affinity (Ser22)	AF3485	Phosphopeptide	Hu\|Ms	WB\|IHC\|IF/ICC\|E

HtrA Serine Peptidase 2 (HTRA2) Antibodies

NS Reagents	AB19-10118	C-terminal peptide	Hu\|Ms\|RT	WB\|IHC
Affinity	DF7626	peptide-central region	Hu	WB\|E
Affinity (Ser212)	AF8275	Phosphopeptide	Hu\|Ms\|Rt	WB\|E
Affinity (Ser142)	AF8381	Phosphopeptide	Hu\|Ms\|Rt	WB\|E

Leucine-Rich Repeat Kinase 2 (LRRK2) Antibodies

Biosensis	R-183-50	aa 946-962	Hu	IHC
Affinity	DF2668	C-terminal	Hu\|Ms	WB\|E
Biosensis	PE-1608			small molecule LRKK2 inhibitor

Nociceptin opioid peptide receptor (OPRL1) Antibodies

NS Reagents	AB18-10069	N-terminal	Hu\|Ms\|Rt	WB
Affinity	DF2834	C-terminal	Hu\|Ms\|Rt	WB

Parkin RBR E3 Ubiquitin Protein Ligase (PRKN/Parkin) Antibodies

Biosensis	R-113-100	aa 305-323	Hu\|Rt	WB\|IHC\|E
Biosensis	R-114-100	aa 295-311	Hu\|Rt	WB\|IHC\|E
Biosensis	PE-1253 (control)	aa 305-323	-	IHC
Affinity	AF0235	Peptide	Hu\|Ms\|Rt	WB\|IHC\|E

PTEN induced kinase 1 (PINK1) Antibodies

Affinity	AF4791	Central region	Hu\|Ms	WB\|E
Affinity	AF7581	Central region	Hu\|Ms\|Rt	WB\|E
Affinity	DF7742	C-terminal	Hu\|Ms\|Rt	WB\|IHC\|E
Affinity (Thr313)	AF4491	Phosphopeptide	Hu\|Ms	WB\|E
Affinity (Ser228)	AF7081	Phosphopeptide	Hu\|Ms\|Rt	WB\|IHC\|E

Ubiquitin Cterminal Hydroxylase 1 (UCHL1/PGP9.5) Antibodies

NS Reagents	AA17-10045	Full length	Hu\|Ms	WB
Biosensis	C-1406-50	Full length	Hu\|Rt\|Ms	WB\|ICC
Biosensis	M-1407-100	Full length	Hu\|Rt\|Ms	WB\|ICC\|IHC
Biosensis	M-1407-100	Full length	Hu\|Rt\|Ms	WB\|ICC
Affinity	AF0243	C-terminal	Hu\|Rt\|Ms	WB\|ICC/IF\|IHC\|E
Affinity	DF6854	C-terminal	Hu\|Rt\|Ms	WB\|ICC/IF\|IHC\|E

Vesicle-associated membrane protein-associated protein B (VAPB) Antibodies

NS Reagents	AB19-10107	Full length	Hu\|Ms	WB\|IHC\|IF
Affinity	DF7303	C-terminal	Hu\|Ms\|Rt	WB\|IHC\|E

Vacuolar protein sorting 35 (VPS35) Antibodies

NS Reagents	AB19-10109	peptide	Hu\|Ms	WB\|IHC
NS Reagents	AB19-10110	N-terminal	Hu\|Ms\|Rt	WB
Affinity	DF12793	Internal region	Hu\|Ms\|Rt	WB

If you are looking for an antibody to a specific target that isn.t listed, please email us as very likely it is in development OR we can always add it to our development list.

Why not work with us on the development of your antibody? We cover ther cost, you do the testing!

Looking for an antibody not listed? Let us know.

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