Newmarket Scientific
Newmarket Scientific








NEWS: Tumour-derived RNA and DNA purification



Exosomics - Solutions for extracellular vesicle  isolation

SeleCTEV-DNA and SoRTEV-RNA for tumour derived DNA and RNA purification

 

The exosomics range provides solutions for the isolation and selective enrichment of tumour-originating extracellular vesicles (EVs) and exosomes from complex biofluids, providing researchers invaluable solutions to detect early cancer hallmarks in blood samples.

 

Current liquid biopsy methods generally isolate total nucleic acids from blood but with only low levels of tumour-derived RNA and DNA. However the Exosomics SeleCTEV-DNA and SoRTEV-RNA kits allow the isolation of tumour-derived genetic material without the need for special equipment, such as ultracentrifugation or chromatography. Using unique proprietary affinity methods these kits selectively purify tumour-derived extracellular vesicles and exosomes from which RNA and DNA can then be extracted.

 

Purification of tumour-originating nucleic acids from tumour enriched EVs and exosomes

 

SoRTEV™ EV-RNA Low Volume (24 rxns)

This kit allows the purification of tumour derived RNA from tumour enriched exosomes in biofluids and includes a user-friendly protocol for RNA purification. The exosome purification is based on immune-affinity beads coated with proprietary antibodies against exosome surface antigens.

SoRTEV

 

SeleCTEV™ EV-DNA Low Volume (24rxn)

This kit allows the purification of both circulating free DNA (cfDNA) and tumour-derived exosome DNA from plasma and/or serum with a starting volume of 0.5 to 2ml. The purification is based on Exosomics proprietary peptide affinity method and this kit includes a user-friendly protocol for DNA purification.

 

SeleCTEV™ EV-DNA High Volume (24rxn)

This kit allows the purification of both circulating free DNA (cfDNA) and tumor-derived exosome DNA from plasma and/or serum with a starting volume of 2 to 7 ml. The purification is based on Exosomics proprietary peptide affinity method and this kit includes a user-friendly protocol for DNA purification.

 

SeleCTEV-HV