Newmarket Scientific
Newmarket Scientific








NS Reagents GBA Antibody



GBA Antibody (Cat No: AB19-10120)

 

Lysosomal acid glucosylceramidase (GBA or Glucocerebrosidase) is the lysosomal hydrolase that hydrolyzes glucosylceramide (GC) and glucosylsphingosine (GS) to ceramide and sphingosine. It is a 536-amino-acid membrane-associated protein with a 39-amino-acid leader sequence that is cleaved to produce a 497-amino-acid mature protein.

 

Mutations in the GBA gene cause Gaucher disease, a lysosomal storage disease characterised by an accumulation of glucocerebrosides. Patients with Gaucher disease and heterozygous carriers are at increased risk of developing Parkinson's disease and Dementia with Lewy Bodies.

 

 

Please contact us for your free sample (tech@nktscientific.com).

 

 


 

 

We need images for this antibody

 

please request your free sample

 

in exchange for images

 

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  GBA Antibody (Cat No: AB19-10120)

 

  Cells:

 

  Technique: IHC

 

  Primary Ab dilution: 1:200

 

 


 


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