Kinesin heavy chain isoform 5A (KIF5A) is an ATPase-active molecular motor protein expressed in neurons that is the heavy chain A of kinesin, A motor protein involved in motility functions within neuron. KIF5A is involved in microtubule-dependent axonal transport of neurofilament proteins (NFH, NFM and NFL). It also contributes to the transport of other proteins in neurons including proteins essential for axon elongation. KIF5A consists of an N-terminal motor domain, a stalk domain and a C-terminal binding domain. The KIF5A gene has been identified as a causative gene in hereditary spastic paraplegia (HSP), Charcot-Marie-Tooth (CMT) type 2 (CMT2) and amyotrophic lateral sclerosis (ALS).
Product Type:
NS Reagents Antibody
Antibody Type:
Polyclonal
Format:
50 µg in 50 µl PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Temp:
Store at -20°C. Avoid freeze / thaw cycles.
Host Animal:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Expected Species:
If you would like us to check if this antibody is likely to bind to this protein from a different species please contact us. We are happy to check for you.
Immunogen:
Partial length recombinant human KIF5A from the C-terminal region
If you would like further information regarding the immunogen used in the production of this antibody or have a query about whether this antibody will bind to your protein/species please contact us and we can do the analysis for you.
Antibody Isotype:
IgG
Application Details:
WB 1:1000-3000. IHC 1:50-200.
Antibody Number:
10081
Category:
Primary Antibodies
Other names:
NKHC, ALS25, MY050, NEIMY, SPG10, D12S1889
Research Areas:
Neuroscience, Amyotrophic lateral sclerosis
NS Reagents Product Area:
Neuroscience
Molecular Weight:
117kDa (Intended as a general guide and does not allow for all isoforms and species variations)
Kinesin heavy chain isoform 5A (KIF5A) is an ATPase-active molecular motor protein expressed in neurons that is the heavy chain A of kinesin, A motor protein involved in motility functions within neuron. KIF5A is involved in microtubule-dependent axonal transport of neurofilament proteins (NFH, NFM and NFL). It also contributes to the transport of other proteins in neurons including proteins essential for axon elongation. KIF5A consists of an N-terminal motor domain, a stalk domain and a C-terminal binding domain. The KIF5A gene has been identified as a causative gene in hereditary spastic paraplegia (HSP), Charcot-Marie-Tooth (CMT) type 2 (CMT2) and amyotrophic lateral sclerosis (ALS).
Product Type:
NS Reagents Antibody
Antibody Type:
Polyclonal
Format:
50 µg in 50 µl PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
Storage Temp:
Store at -20°C. Avoid freeze / thaw cycles.
Host Animal:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Expected Species:
If you would like us to check if this antibody is likely to bind to this protein from a different species please contact us. We are happy to check for you.
Immunogen:
A synthetic peptide from the C-terminal region of human KIF5A
If you would like further information regarding the immunogen used in the production of this antibody or have a query about whether this antibody will bind to your protein/species please contact us and we can do the analysis for you.
Antibody Isotype:
IgG
Application Details:
IHC 1:50-100.
Antibody Number:
10082
Category:
Primary Antibodies
Other names:
NKHC, ALS25, MY050, NEIMY, SPG10, D12S1889
Research Areas:
Neuroscience, Amyotrophic lateral sclerosis
NS Reagents Product Area:
Neuroscience
Molecular Weight:
117kDa (Intended as a general guide and does not allow for all isoforms and species variations)
Kinesin heavy chain isoform 5A (KIF5A) is an ATPase-active molecular motor protein expressed in neurons that is the heavy chain A of kinesin, A motor protein involved in motility functions within neuron. KIF5A is involved in microtubule-dependent axonal transport of neurofilament proteins (NFH, NFM and NFL). It also contributes to the transport of other proteins in neurons including proteins essential for axon elongation. KIF5A consists of an N-terminal motor domain, a stalk domain and a C-terminal binding domain. The KIF5A gene has been identified as a causative gene in hereditary spastic paraplegia (HSP), Charcot-Marie-Tooth (CMT) type 2 (CMT2) and amyotrophic lateral sclerosis (ALS).
Product Type:
NS Reagents Antibody
Antibody Type:
Polyclonal
Format:
100 µg in 100 µl PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Temp:
Store at -20°C. Avoid freeze / thaw cycles.
Host Animal:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Expected Species:
If you would like us to check if this antibody is likely to bind to this protein from a different species please contact us. We are happy to check for you.
Immunogen:
Partial length recombinant human KIF5A from the C-terminal region
If you would like further information regarding the immunogen used in the production of this antibody or have a query about whether this antibody will bind to your protein/species please contact us and we can do the analysis for you.
Antibody Isotype:
IgG
Application Details:
WB 1:1000-3000. IHC 1:50-200.
Antibody Number:
10081
Category:
Primary Antibodies
Other names:
NKHC, ALS25, MY050, NEIMY, SPG10, D12S1889
Research Areas:
Neuroscience, Amyotrophic lateral sclerosis
NS Reagents Product Area:
Neuroscience
Molecular Weight:
117kDa (Intended as a general guide and does not allow for all isoforms and species variations)
Kinesin heavy chain isoform 5A (KIF5A) is an ATPase-active molecular motor protein expressed in neurons that is the heavy chain A of kinesin, A motor protein involved in motility functions within neuron. KIF5A is involved in microtubule-dependent axonal transport of neurofilament proteins (NFH, NFM and NFL). It also contributes to the transport of other proteins in neurons including proteins essential for axon elongation. KIF5A consists of an N-terminal motor domain, a stalk domain and a C-terminal binding domain. The KIF5A gene has been identified as a causative gene in hereditary spastic paraplegia (HSP), Charcot-Marie-Tooth (CMT) type 2 (CMT2) and amyotrophic lateral sclerosis (ALS).
Product Type:
NS Reagents Antibody
Antibody Type:
Polyclonal
Format:
100 µg in 100 µl PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
Storage Temp:
Store at -20°C. Avoid freeze / thaw cycles.
Host Animal:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Expected Species:
If you would like us to check if this antibody is likely to bind to this protein from a different species please contact us. We are happy to check for you.
Immunogen:
A synthetic peptide from the C-terminal region of human KIF5A
If you would like further information regarding the immunogen used in the production of this antibody or have a query about whether this antibody will bind to your protein/species please contact us and we can do the analysis for you.
Antibody Isotype:
IgG
Application Details:
IHC 1:50-100.
Antibody Number:
10082
Category:
Primary Antibodies
Other names:
NKHC, ALS25, MY050, NEIMY, SPG10, D12S1889
Research Areas:
Neuroscience, Amyotrophic lateral sclerosis
NS Reagents Product Area:
Neuroscience
Molecular Weight:
117kDa (Intended as a general guide and does not allow for all isoforms and species variations)
Subcellular location:
Cytoplasm
Purification:
Affinity purification
Uniprot ID:
Q12840
Gene ID:
3798
Gene symbol:
KIF5A
Release Date:
May-19
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