Newmarket Scientific Product Search Results for AB19-10120

Product Search Results: AB19-10120
Num Products Matched:
Product Search Results: AB19-10120	Num Products Matched: 2	2

Newmarket Scientific - NS Reagents

AB19-10120-50ug

50 µg

£225.00

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Product Detail:	Anti-GBA Antibody (Polyclonal)
Background Info:	Lysosomal acid glucosylceramidase (GBA or Glucocerebrosidase) is the lysosomal hydrolase that hydrolyzes glucosylceramide (GC) and glucosylsphingosine (GS) to ceramide and sphingosine. It is a 536-amino-acid membrane-associated protein with a 39-amino-acid leader sequence that is cleaved to produce a 497-amino-acid mature protein. Mutations in the GBA gene cause Gaucher disease, a lysosomal storage disease characterised by an accumulation of glucocerebrosides. Patients with Gaucher disease and heterozygous carriers are at increased risk of developing Parkinson's disease and Dementia with Lewy Bodies.
Product Type:	NS Reagents Antibody
Antibody Type:	Polyclonal
Format:	50 µg in 50 µl PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Temp:	6 months: 4°C. Long-term storage: -20°C. Avoid multiple freeze and thaw cycles.
Host Animal:	Rabbit
Species Reactivity:	Human
Expected Species:	Mouse, Rat, Pig, Bovine, Pig, Dog, Horse
Immunogen:	Full length recombinant human GBA
Applications:	WB ¦ IHC
Data Sheet:	PLEASE CLICK HERE TO DOWNLOAD
Additional Info:	If you would like further information regarding the immunogen used in the production of this antibody or have a query about whether this antibody will bind to your protein/species please contact us and we can do the analysis for you.
Antibody Isotype:	IgG
Application Details:	WB 1:500-2000. IHC 1:50-200.
Category:	Primary Antibodies
Other names:	GBA, GCB, GLUC, Lysosomal acid glucosylceramidase, Lysosomal acid GCase, Acid beta-glucosidase, Alglucerase, Beta-glucocerebrosidase, Cholesterol glucosyltransferase, D-glucosyl-N-acylsphingosine glucohydrolase, Imiglucerase, lysosomal enzyme glucocerebrosidase, Glucosylceramidase Beta, GCase, EC 3.2.1.45
Research Areas:	Neuroscience
NS Reagents Product Area:	Neuroscience
Molecular Weight:	60kDa (Intended as a general guide and does not allow for all isoforms and species variations)
Subcellular location:	Lysosome
Purification:	Affinity purification
Uniprot ID:	P04062
Gene ID:	2629
Gene symbol:	GBA
Release Date:	Sep-19

Newmarket Scientific - NS Reagents

AB19-10120-100ug

100 µg

£295.00

Please sign in or sign up to order this product online.

Product Detail:	Anti-GBA Antibody (Polyclonal)
Background Info:	Lysosomal acid glucosylceramidase (GBA or Glucocerebrosidase) is the lysosomal hydrolase that hydrolyzes glucosylceramide (GC) and glucosylsphingosine (GS) to ceramide and sphingosine. It is a 536-amino-acid membrane-associated protein with a 39-amino-acid leader sequence that is cleaved to produce a 497-amino-acid mature protein. Mutations in the GBA gene cause Gaucher disease, a lysosomal storage disease characterised by an accumulation of glucocerebrosides. Patients with Gaucher disease and heterozygous carriers are at increased risk of developing Parkinson's disease and Dementia with Lewy Bodies.
Product Type:	NS Reagents Antibody
Antibody Type:	Polyclonal
Format:	100 µg in 100 µl PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Temp:	6 months: 4°C. Long-term storage: -20°C. Avoid multiple freeze and thaw cycles.
Host Animal:	Rabbit
Species Reactivity:	Human
Expected Species:	Mouse, Rat, Pig, Bovine, Pig, Dog, Horse
Immunogen:	Full length recombinant human GBA
Applications:	WB ¦ IHC
Data Sheet:	PLEASE CLICK HERE TO DOWNLOAD
Additional Info:	If you would like further information regarding the immunogen used in the production of this antibody or have a query about whether this antibody will bind to your protein/species please contact us and we can do the analysis for you.
Antibody Isotype:	IgG
Application Details:	WB 1:500-2000. IHC 1:50-200.
Category:	Primary Antibodies
Other names:	GBA, GCB, GLUC, Lysosomal acid glucosylceramidase, Lysosomal acid GCase, Acid beta-glucosidase, Alglucerase, Beta-glucocerebrosidase, Cholesterol glucosyltransferase, D-glucosyl-N-acylsphingosine glucohydrolase, Imiglucerase, lysosomal enzyme glucocerebrosidase, Glucosylceramidase Beta, GCase, EC 3.2.1.45
Research Areas:	Neuroscience
NS Reagents Product Area:	Neuroscience
Molecular Weight:	60kDa (Intended as a general guide and does not allow for all isoforms and species variations)
Subcellular location:	Lysosome
Purification:	Affinity purification
Uniprot ID:	P04062
Gene ID:	2629
Gene symbol:	GBA
Release Date:	Sep-19

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Product Search Results: AB19-10120

Product Search Results: AB19-10120

Anti-GBA Antibody

Anti-GBA Antibody