Newmarket Scientific Product Search Results for anti-G3BP1

Product Search Results: anti-G3BP1
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Product Search Results: anti-G3BP1	Num Products Matched: 2	2

Newmarket Scientific - NS Reagents

AB19-10113-100ug

100 µg

£275.00

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Product Detail:	Anti-G3BP1 Antibody (Polyclonal)
Background Info:	Ras GTPase-activating protein-binding protein 1 (G3BP1) is a RNA-binding protein which along with G3BP2 regulates stress granule (SG) formation. Both G3BP1 & 2 contain disordered regions and an ordered nuclear transport factor 2 (NTF2)-like dimerisation domain at the N-terminal that is that is required for SG formation. G3BP1 has endoribonuclease and helicase activity and is part of the Ras signal transduction pathway, binding specifically to Ras-GTPase-activating protein via its SH3 domain. G3BP1 has multiple phosphorylation sites which may be involved in its function in regulating stress granules. SG-like structures have been reported in neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), so it is believed that G3BP1 may play a role in such neurodegenerative diseases.
Product Type:	NS Reagents Antibody
Antibody Type:	Polyclonal
Format:	100 µg in 100 µl PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Temp:	6 months: 4°C. Long-term storage: -20°C. Avoid multiple freeze and thaw cycles.
Host Animal:	Rabbit
Species Reactivity:	Human, Mouse, Duck
Expected Species:	Rat, Cow, Chicken, Guinea Pig, Zebra finch, Goat, Dog, Cat If you would like us to check if this antibody is likely to bind to this protein from a different species please contact us. We are happy to check for you.
Immunogen:	Partial length recombinant human G3BP1 from the C-terminal region
Applications:	WB ¦ IHC ¦ IF
Data Sheet:	PLEASE CLICK HERE TO DOWNLOAD
Additional Info:	If you would like further information regarding the immunogen used in the production of this antibody or have a query about whether this antibody will bind to your protein/species please contact us and we can do the analysis for you.
Antibody Isotype:	IgG
Application Details:	WB 1:500-2000. IHC 1:50-200. IF 1:50-200.
Category:	Primary Antibodies
Other names:	G3BP, HDH-VIII, ATP-dependent DNA helicase VIII, GAP SH3 domain-binding protein 1, G3BP-1
Research Areas:	Neuroscience
NS Reagents Product Area:	Neuroscience
Peptide Sequence (Internal Use only):	AQKSSSPAPADIAQTVQEDLRTFSWASVTSKNLPPSGAVPVTGIPPHVVKVPASQPRPESKPESQIPPQRPQRDQRVREQRINIPPQRGPRPIREAGEQGDIEPRRMVRHPDSHQLFIGNLPHEVDKSELKDFFQSYGNVVELRINSGGKLPNFGFVVFDDSEPVQKVLSNRPIMFRGEVRLNVEEKKTRAAREGDRRDNRLRGPGGPRGGLGGGMRGPPRGGMVQKPGFGVGRGLAPRQ Recombinant fusion protein containing a sequence corresponding to amino acids 227-466 of human G3BP1 Full Protein is 466 aa in length 10 20 30 40 50 MVMEKPSPLL VGREFVRQYY TLLNQAPDML HRFYGKNSSY VHGGLDSNGK 60 70 80 90 100 PADAVYGQKE IHRKVMSQNF TNCHTKIRHV DAHATLNDGV VVQVMGLLSN 110 120 130 140 150 NNQALRRFMQ TFVLAPEGSV ANKFYVHNDI FRYQDEVFGG FVTEPQEESE 160 170 180 190 200 EEVEEPEERQ QTPEVVPDDS GTFYDQAVVS NDMEEHLEEP VAEPEPDPEP 210 220 230 240 250 EPEQEPVSEI QEEKPEPVLE ETAPEDAQKS SSPAPADIAQ TVQEDLRTFS 260 270 280 290 300 WASVTSKNLP PSGAVPVTGI PPHVVKVPAS QPRPESKPES QIPPQRPQRD 310 320 330 340 350 QRVREQRINI PPQRGPRPIR EAGEQGDIEP RRMVRHPDSH QLFIGNLPHE 360 370 380 390 400 VDKSELKDFF QSYGNVVELR INSGGKLPNF GFVVFDDSEP VQKVLSNRPI 410 420 430 440 450 MFRGEVRLNV EEKKTRAARE GDRRDNRLRG PGGPRGGLGG GMRGPPRGGM 460 VQKPGFGVGR GLAPRQ
Molecular Weight:	52kDa (Intended as a general guide and does not allow for all isoforms and species variations)
Subcellular location:	Stress granule, Nucleus, Cytosol, Perikaryon
Purification:	Affinity purification
Uniprot ID:	Q13283
Gene ID:	10146
Gene symbol:	G3BP1
Release Date:	September 2019

Newmarket Scientific - NS Reagents

AB19-10113-50ug

50 µg

£220.00

Please sign in or sign up to order this product online.

Product Detail:	Anti-G3BP1 Antibody (Polyclonal)
Background Info:	Ras GTPase-activating protein-binding protein 1 (G3BP1) is a RNA-binding protein which along with G3BP2 regulates stress granule (SG) formation. Both G3BP1 & 2 contain disordered regions and an ordered nuclear transport factor 2 (NTF2)-like dimerisation domain at the N-terminal that is that is required for SG formation. G3BP1 has endoribonuclease and helicase activity and is part of the Ras signal transduction pathway, binding specifically to Ras-GTPase-activating protein via its SH3 domain. G3BP1 has multiple phosphorylation sites which may be involved in its function in regulating stress granules. SG-like structures have been reported in neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), so it is believed that G3BP1 may play a role in such neurodegenerative diseases.
Product Type:	NS Reagents Antibody
Antibody Type:	Polyclonal
Format:	50 µg in 50 µl PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Temp:	6 months: 4°C. Long-term storage: -20°C. Avoid multiple freeze and thaw cycles.
Host Animal:	Rabbit
Species Reactivity:	Human, Mouse, Duck
Expected Species:	Rat, Cow, Chicken, Guinea Pig, Zebra finch, Goat, Dog, Cat If you would like us to check if this antibody is likely to bind to this protein from a different species please contact us. We are happy to check for you.
Immunogen:	Partial length recombinant human G3BP1 from the C-terminal region
Applications:	WB ¦ IHC ¦ IF
Data Sheet:	PLEASE CLICK HERE TO DOWNLOAD
Additional Info:	If you would like further information regarding the immunogen used in the production of this antibody or have a query about whether this antibody will bind to your protein/species please contact us and we can do the analysis for you.
Antibody Isotype:	IgG
Application Details:	WB 1:500-2000. IHC 1:50-200. IF 1:50-200.
Category:	Primary Antibodies
Other names:	G3BP, HDH-VIII, ATP-dependent DNA helicase VIII, GAP SH3 domain-binding protein 1, G3BP-1
Research Areas:	Neuroscience
NS Reagents Product Area:	Neuroscience
Peptide Sequence (Internal Use only):	AQKSSSPAPADIAQTVQEDLRTFSWASVTSKNLPPSGAVPVTGIPPHVVKVPASQPRPESKPESQIPPQRPQRDQRVREQRINIPPQRGPRPIREAGEQGDIEPRRMVRHPDSHQLFIGNLPHEVDKSELKDFFQSYGNVVELRINSGGKLPNFGFVVFDDSEPVQKVLSNRPIMFRGEVRLNVEEKKTRAAREGDRRDNRLRGPGGPRGGLGGGMRGPPRGGMVQKPGFGVGRGLAPRQ Recombinant fusion protein containing a sequence corresponding to amino acids 227-466 of human G3BP1 Full Protein is 466 aa in length 10 20 30 40 50 MVMEKPSPLL VGREFVRQYY TLLNQAPDML HRFYGKNSSY VHGGLDSNGK 60 70 80 90 100 PADAVYGQKE IHRKVMSQNF TNCHTKIRHV DAHATLNDGV VVQVMGLLSN 110 120 130 140 150 NNQALRRFMQ TFVLAPEGSV ANKFYVHNDI FRYQDEVFGG FVTEPQEESE 160 170 180 190 200 EEVEEPEERQ QTPEVVPDDS GTFYDQAVVS NDMEEHLEEP VAEPEPDPEP 210 220 230 240 250 EPEQEPVSEI QEEKPEPVLE ETAPEDAQKS SSPAPADIAQ TVQEDLRTFS 260 270 280 290 300 WASVTSKNLP PSGAVPVTGI PPHVVKVPAS QPRPESKPES QIPPQRPQRD 310 320 330 340 350 QRVREQRINI PPQRGPRPIR EAGEQGDIEP RRMVRHPDSH QLFIGNLPHE 360 370 380 390 400 VDKSELKDFF QSYGNVVELR INSGGKLPNF GFVVFDDSEP VQKVLSNRPI 410 420 430 440 450 MFRGEVRLNV EEKKTRAARE GDRRDNRLRG PGGPRGGLGG GMRGPPRGGM 460 VQKPGFGVGR GLAPRQ
Molecular Weight:	52kDa (Intended as a general guide and does not allow for all isoforms and species variations)
Subcellular location:	Stress granule, Nucleus, Cytosol, Perikaryon
Purification:	Affinity purification
Uniprot ID:	Q13283
Gene ID:	10146
Gene symbol:	G3BP1
Release Date:	September 2019

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Product Search Results: anti-G3BP1

Product Search Results: anti-G3BP1

Anti-G3BP1 Antibody

Anti-G3BP1 Antibody