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Product Search Results: AA17-10047

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Product Search Results: AA17-10047

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Newmarket Scientific - NS Reagents AA17-10047-50ul 50 µl £258.00
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Product Detail: Anti-BFAR Antibody (Polyclonal - Sera)
Background Info: Bifunctional apoptosis regulator (BFAR/BAR) is a multidomain protein originally identified as an inhibitor of Bax-induced apoptosis. It is predominantly found in the endoplasmic reticulum (ER) and is thought to be a scaffold protein that may bridge components of both extrinsic and intrinsic apoptosis pathways.

BFAR contains a DED (death effector domain) like domain that suppresses death receptor apoptosis signalling pathways. It is highly expressed in the brain and is believed to be involved in regulating neuronal survival, helping neurons to survive for the entire lifetime of the organism by playing a central role in inhibiting ER initiated apoptosis.
Product Type: NS Reagents Antibody
Antibody Type: Polyclonal
Format: Sera with Sodium Azide
Storage Temp: 6 months: 4°C. Long-term storage: -20°C. Avoid multiple freeze and thaw cycles.
Host Animal: Rabbit
Species Reactivity: Human
Expected Species: This antibody is not expected to bind to Bifunctional apoptosis regulator from other species. The immunogens was epcifically selected for this purpose.

If you would like us to check if this antibody is likely to bind to this protein from a different species please contact us. We are happy to check for you.
Immunogen: A synthetic peptide from the N-terminal region of Human BFAR (BAR)
Applications: IP ¦ IHC ¦ WB
Additional Info: If you would like further information regarding the immunogen used in the production of this antibody or have a query about whether this antibody will bind to your protein/species please contact us and we can do the analysis for you.
Antibody Isotype: IgG
Application Details: WB: 1:1000-1:2000
IHC (paraffin): 1:1000-1:5000
IHC (frozen): 1:1000-1:2000
IP: 1:50-1:200
Category: Primary Antibodies
Other names: Bifunctional apoptosis regulator, BFAR, BAR, RNF47
Research Areas: Neuroscience
NS Reagents Product Area: Neuroscience
Molecular Weight: 53kDa (Intended as a general guide and does not allow for all isoforms and species variations)
Subcellular location: Endoplasmic reticulum membrane
Purification: Sera
Uniprot ID: Q9NZS9
Gene ID: 51283
Gene symbol: BFAR
Release Date: Dec-17