| Product Detail: |
Anti-MFN2 Antibody (Polyclonal) |
| Background Info: |
Mitofusin-2 (MFN2) is a mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion and contributes to the maintenance and operation of the mitochondrial network. MFN2 is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. |
| Product Type: |
NS Reagents Antibody |
| Antibody Type: |
Polyclonal |
| Format: |
100 µg in 100 µl PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| Storage Temp: |
6 months: 4°C. Long-term storage: -20°C. Avoid multiple freeze and thaw cycles. |
| Host Animal: |
Rabbit |
| Species Reactivity: |
Human |
| Expected Species: |
Mouse, Rat, Rabbit, Chicken, Guinea Pig, Chinese Hamster, Cat, Rainbow Trout, Turbot, Naked Mole Rat, Cuckoo and many other species
If you would like us to check if this antibody is likely to bind to this protein from a different species please contact us. We are happy to check for you. |
| Immunogen: |
A synthetic peptide of 13 aa taken from human MFN2 between aa 100 and 300 |
| Applications: |
WB ¦ IHC |
| Data Sheet: |
PLEASE CLICK HERE TO DOWNLOAD |
| Additional Info: |
If you would like further information regarding the immunogen used in the production of this antibody or have a query about whether this antibody will bind to your protein/species please contact us and we can do the analysis for you. |
| Antibody Isotype: |
IgG |
| Application Details: |
WB 1:1000-4000. IHC 1:50-200 |
| Category: |
Primary Antibodies |
| Other names: |
CMT2A, CMT2A2, CMT2A2A, CMT2A2B, CPRP1, HMSN6A, HSG, KIAA0214, MARF, Mitofusin 2, Transmembrane GTPase MFN2 |
| Research Areas: |
Neuroscience, NSReagents Alzheimer's / Parkinson's |
| NS Reagents Product Area: |
Neuroscience |
| Molecular Weight: |
86kDa (Intended as a general guide and does not allow for all isoforms and species variations) |
| Subcellular location: |
Cytoplasm Cell membrane, Mitochondrion outer membrane |
| Purification: |
Affinity purification |
| Uniprot ID: |
O95140 |
| Gene ID: |
9927 |
| Gene symbol: |
MFN2 |
| Release Date: |
Oct-18 |
