Solute carrier family 2, facilitated glucose transporter member 4 (SLC2A4, GLUT4) is an insulin-regulated glucose transporter found primarily in adipose tissues and striated muscle (skeletal and cardiac). It facilitates the diffusion of circulating glucose down its concentration gradient into muscle and fat cells, playing a key role in removal of glucose from circulation with the response to insulin being regulated by its intracellular localisation. In the absence of insulin, it is retained intracellularly within storage compartments in muscle and fat cells and following insulin stimulation it translocates to the cell surface. SLC2A4 has a phenylalanine on the N-terminus and two Leucine residues and acidic motifs on the C-terminus which are believed to play a key role in its glucose transport function.
Product Type:
NS Reagents Antibody
Antibody Type:
Polyclonal
Format:
50 µg in 50 µl PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
If you would like us to check if this antibody is likely to bind to this protein from a different species please contact us. We are happy to check for you.
Immunogen:
Partial length recombinant human GTR4 (SLC2A4) from the C-terminal region
If you would like further information regarding the immunogen used in the production of this antibody or have a query about whether this antibody will bind to your protein/species please contact us and we can do the analysis for you.
Antibody Isotype:
IgG
Application Details:
WB 1:500-2000. IHC 1:50-200.
Category:
Primary Antibodies
Other names:
GLUT4, SLC2A4, GEF, HDBP 1, SLC2A4RG, glucose transporter type 4, insulin-responsive glucose transporter type 4, solute carrier family 2, facilitated glucose transporter member 4
Research Areas:
Neuroscience, Diabetes
NS Reagents Product Area:
Neuroscience
Molecular Weight:
55kDa (Intended as a general guide and does not allow for all isoforms and species variations)
Subcellular location:
Cell membrane, Cytoplasm, Endomembrane system, Multi-pass membrane protein, perinuclear region
Solute carrier family 2, facilitated glucose transporter member 4 (SLC2A4, GLUT4) is an insulin-regulated glucose transporter found primarily in adipose tissues and striated muscle (skeletal and cardiac). It facilitates the diffusion of circulating glucose down its concentration gradient into muscle and fat cells, playing a key role in removal of glucose from circulation with the response to insulin being regulated by its intracellular localisation. In the absence of insulin, it is retained intracellularly within storage compartments in muscle and fat cells and following insulin stimulation it translocates to the cell surface. SLC2A4 has a phenylalanine on the N-terminus and two Leucine residues and acidic motifs on the C-terminus which are believed to play a key role in its glucose transport function.
Product Type:
NS Reagents Antibody
Antibody Type:
Polyclonal
Format:
100 µg in 100 µl PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
If you would like us to check if this antibody is likely to bind to this protein from a different species please contact us. We are happy to check for you.
Immunogen:
Partial length recombinant human GTR4 (SLC2A4) from the C-terminal region
If you would like further information regarding the immunogen used in the production of this antibody or have a query about whether this antibody will bind to your protein/species please contact us and we can do the analysis for you.
Antibody Isotype:
IgG
Application Details:
WB 1:500-2000. IHC 1:50-200.
Category:
Primary Antibodies
Other names:
GLUT4, SLC2A4, GEF, HDBP 1, SLC2A4RG, glucose transporter type 4, insulin-responsive glucose transporter type 4, solute carrier family 2, facilitated glucose transporter member 4
Research Areas:
Neuroscience, Diabetes
NS Reagents Product Area:
Neuroscience
Molecular Weight:
55kDa (Intended as a general guide and does not allow for all isoforms and species variations)
Subcellular location:
Cell membrane, Cytoplasm, Endomembrane system, Multi-pass membrane protein, perinuclear region
Purification:
Affinity purification
Uniprot ID:
P14672
Gene ID:
6517
Gene symbol:
SLC2A4
Release Date:
Jan-19
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