Nogo receptor 3 (NgR3) is a 441 amino acid protein that belongs to the Nogo receptor family. Nogo receptors NgR1, NgR2 and NgR3 are Glycosylphosphatidylinositol-anchored proteins (GPI-APs) that share similar structures, including eight leucine-rich repeats (LRRs) between N-terminal and C-terminal LRR-capping domains, connected via a stalk region to the GPI anchor.
NgR3 is predominantly expressed in brain, where it localises to the surface of neurons, but is also found at lower levels in lung, placenta, kidney, mammary gland, skeletal muscle, spleen and salivary gland.
NgR1 binds to three myelin inhibitors Nogo, OMgp, and Myelin-associated-glycoprotein (MAG), whereas NgR2 interacts with MAG. The ligands that bind to NgR3 are less clear.
Product Type:
NS Reagents Antibody
Antibody Type:
Polyclonal Antibody
Format:
50 µg in 50 µl PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
If you would like us to check if this antibody is likely to bind to this protein from a different species please contact us. We are happy to check for you.
If you would like further information regarding the immunogen used in the production of this antibody or have a query about whether this antibody will bind to your protein/species please contact us and we can do the analysis for you.
Nogo receptor 3 (NgR3) is a 441 amino acid protein that belongs to the Nogo receptor family. Nogo receptors NgR1, NgR2 and NgR3 are Glycosylphosphatidylinositol-anchored proteins (GPI-APs) that share similar structures, including eight leucine-rich repeats (LRRs) between N-terminal and C-terminal LRR-capping domains, connected via a stalk region to the GPI anchor.
NgR3 is predominantly expressed in brain, where it localises to the surface of neurons, but is also found at lower levels in lung, placenta, kidney, mammary gland, skeletal muscle, spleen and salivary gland.
NgR1 binds to three myelin inhibitors Nogo, OMgp, and Myelin-associated-glycoprotein (MAG), whereas NgR2 interacts with MAG. The ligands that bind to NgR3 are less clear.
Product Type:
NS Reagents Antibody
Antibody Type:
Polyclonal Antibody
Format:
100 µg in 100 µl PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
If you would like us to check if this antibody is likely to bind to this protein from a different species please contact us. We are happy to check for you.
If you would like further information regarding the immunogen used in the production of this antibody or have a query about whether this antibody will bind to your protein/species please contact us and we can do the analysis for you.
AB20-10132-50ug Anti-Lipocalin-2 Antibody (Polyclonal) £220 AB20-10129-100ug Anti-Reticulon-4 receptor-like 1 Antibody (Polyclonal) £275 And others as discussed
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