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ImmunoStar 24430 100uL £351.00
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Product Detail: 5-HT (Serotonin) 7 Receptor Antibody
Background Info: Raised against synthetic peptide sequence corresponding to amino acids 8-23 of the rat 5-HT7 receptor coupled to carrier protein with glutaraldehyde.
Product Type: Antibody - Antibodies
Antibody Type: polyclonal
Format: Liquid
Host Animal: Rabbit
Species Reactivity: Rat, Mouse
Immunogen: Rat 5-HT7 receptor (8-23)
Applications: Immunohistochemistry, Immunocytochemistry, immunofluorescence, Northern blot
Data Sheet: PLEASE CLICK HERE TO DOWNLOAD
Additional Info: The 5-HT7 Receptor Antibody was raised against synthetic peptide sequence corresponding to amino acids 8-23 of the rat 5-HT7 receptor coupled to carrier protein with glutaraldehyde. The ImmunoStar 5-HT7 receptor antiserum was quality control tested using standard immunohistochemical methods. The antiserum demonstrates strongly positive labeling of rat cortex and hippocampus using indirect immunofluorescent and biotin/avidin-HRP techniques. Recommended primary dilutions are 1/100 - 1/300 in PBS - biotin/avidin-HRP Technique. Note: use of Triton X-100 or other detergents is not recommended.

The antibody was characterized by immunohistochemistry. Immunohistochemical staining of rat brain correlates well with Northern blot analysis, in situ hybridization and receptor autoradiography studies. Immunolabeling is completely abolished by preadsorption with synthetic rat 5-HT7 receptor (8-23). BlastP database sequence homology searches indicate that the amino acid sequence is unique to rat 5-HT7A, 5-HT7B and 5-HT7C. There is also significant sequence overlap with the mouse and human forms.