Newmarket Scientific
Newmarket Scientific

Product Search Results: AB18-10062 (100ug)

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Product Search Results: AB18-10062 (100ug)

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Newmarket Scientific - NS Reagents AB18-10062-100ug 100ug £275.00
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Product Detail: Anti-RAMP3 Polyclonal Antibody
Background Info: Receptor Activity Modifying Protein 3 (RAMP3) is a member of the RAMP family of single-transmembrane-domain proteins, which are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus.

RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed.

In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor.
Product Type: NS Reagents Antibody
Antibody Type: Polyclonal
Format: 100 µg in 100 µl PBS containing 0.02% sodium azide.
Storage Temp: 6 months: 4°C. Long-term storage: -20°C. Avoid multiple freeze and thaw cycles.
Host Animal: Rabbit
Species Reactivity: Human Mouse Rat
Immunogen: Recombinant human RAMP3
Applications: WB IF
Alternative Name: RAMP3, Receptor Activity Modifying Protein 3, Calcitonin Receptor-Like Receptor Activity Modifying Protein 3
Antibody Isotype: IgG
Application Details: WB 1:500-2000. IF 1:10-100.
Category: Primary Antibodies
Research Areas: Cell Signalling and Transport, calcitonin-receptor-like receptor
NS Reagents Product Area: Cell Signalling
Molecular Weight: 17kDa
Subcellular location: Cell membrane, Membrane, Single-pass type I membrane protein
Purification: Affinity purification
Uniprot ID: O60896
Gene ID: 10268
Release Date: Nov-18