Newmarket Scientific Product Search Results for AX17-10008

Product Search Results: AX17-10008
Num Products Matched:
Product Search Results: AX17-10008	Num Products Matched: 2	2

Newmarket Scientific - NS Reagents

AX17-10008-50ug

50 µg

220

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Product Detail:	Anti-Cytochrome P450 7B1 (Clone M17-P3F2)
Background Info:	Cytochrome P450 7B1 (25-hydroxycholesterol 7alpha-hydroxylase) is a member of the cytochrome P450 superfamily of enzymes involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. In the liver CYP7B1 most likely only plays a minor role in total bile acid synthesis, providing an alternate acidic pathway for the formation of bile acids through cholesterol degradation. In the brain CYP7B1 is important in the metabolism of brain cholesterol. As there is little or no transfer of cholesterol across the blood-brain barrier, cholesterol must be produced in the brain locally, and CYP7B1 is important in maintaining the precise balance between the biosynthesis, storage, and catabolism of cholesterol metabolites.
Product Type:	NS Reagents Antibody
Antibody Type:	Monoclonal
Format:	50 µg in 50 µl PBS containing 0.02% sodium azide.
Storage Temp:	6 months: 4°C. Long-term storage: -20°C. Avoid multiple freeze and thaw cycles.
Host Animal:	Mouse
Species Reactivity:	Human
Expected Species:	If you would like us to check if this antibody is likely to bind to this protein from a different species please contact us. We are happy to check for you.
Immunogen:	Ovalbumin-conjugated synthetic peptide from the C-terminal region of Human
Applications:	ELISA ¦ IHC ¦ WB
Data Sheet:	PLEASE CLICK HERE TO DOWNLOAD
Additional Info:	If you would like further information regarding the immunogen used in the production of this antibody or have a query about whether this antibody will bind to your protein/species please contact us and we can do the analysis for you.
Clone number:	Clone M17-P3F2
Antibody Isotype:	IgG1 lambda
Category:	Primary Antibodies
Other names:	25-hydroxycholesterol 7-alpha-hydroxylase, CP7B, CP7B1, oxysterol 7-alpha-hydroxylase, CYP450 7B1
Research Areas:	Neuroscience, cholesterol
NS Reagents Product Area:	Neuroscience
Molecular Weight:	59kDa (Intended as a general guide and does not allow for all isoforms and species variations)
Subcellular location:	Endoplasmic reticulum
Purification:	Protein A Affinity Purified
References:	Swan et al. 2016. Oncotarget. :. PMID: 27341022.
Uniprot ID:	O75881
Gene ID:	9420
Gene symbol:	CYP7B1
Release Date:	Oct-17

Newmarket Scientific - NS Reagents

AX17-10008-100ug

100 µg

275

Please sign in or sign up to order this product online.

Product Detail:	Anti-Cytochrome P450 7B1 (Clone M17-P3F2)
Background Info:	Cytochrome P450 7B1 (25-hydroxycholesterol 7alpha-hydroxylase) is a member of the cytochrome P450 superfamily of enzymes involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. In the liver CYP7B1 most likely only plays a minor role in total bile acid synthesis, providing an alternate acidic pathway for the formation of bile acids through cholesterol degradation. In the brain CYP7B1 is important in the metabolism of brain cholesterol. As there is little or no transfer of cholesterol across the blood-brain barrier, cholesterol must be produced in the brain locally, and CYP7B1 is important in maintaining the precise balance between the biosynthesis, storage, and catabolism of cholesterol metabolites.
Product Type:	NS Reagents Antibody
Antibody Type:	Monoclonal
Format:	100 µg in 100 µl PBS containing 0.02% sodium azide.
Storage Temp:	6 months: 4°C. Long-term storage: -20°C. Avoid multiple freeze and thaw cycles.
Host Animal:	Mouse
Species Reactivity:	Human
Expected Species:	If you would like us to check if this antibody is likely to bind to this protein from a different species please contact us. We are happy to check for you.
Immunogen:	Ovalbumin-conjugated synthetic peptide from the C-terminal region of Human
Applications:	ELISA ¦ IHC ¦ WB
Data Sheet:	PLEASE CLICK HERE TO DOWNLOAD
Additional Info:	If you would like further information regarding the immunogen used in the production of this antibody or have a query about whether this antibody will bind to your protein/species please contact us and we can do the analysis for you.
Clone number:	Clone M17-P3F2
Antibody Isotype:	IgG1 lambda
Category:	Primary Antibodies
Other names:	25-hydroxycholesterol 7-alpha-hydroxylase, CP7B, CP7B1, oxysterol 7-alpha-hydroxylase, CYP450 7B1
Research Areas:	Neuroscience, cholesterol
NS Reagents Product Area:	Neuroscience
Molecular Weight:	59kDa (Intended as a general guide and does not allow for all isoforms and species variations)
Subcellular location:	Endoplasmic reticulum
Purification:	Protein A Affinity Purified
References:	Swan et al. 2016. Oncotarget. :. PMID: 27341022.
Uniprot ID:	O75881
Gene ID:	9420
Gene symbol:	CYP7B1
Release Date:	Oct-17

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Product Search Results: AX17-10008

Product Search Results: AX17-10008

Anti-Cytochrome P450 7B1 Antibody

Anti-Cytochrome P450 7B1 Antibody