Newmarket Scientific Product Search Results for BSH-3004

Product Search Results: BSH-3004
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Product Search Results: BSH-3004	Num Products Matched: 2	2

Product - please click for more details

Optibodies - Nordic BioSite

BSH-3004-100

100 µl

£210.00

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Product Detail:	The human leukocyte differentiation antigen CD23 (FCER2) is a key molecule for B-cell activation and growth. It is the low-affinity receptor for IgE. The truncated molecule can be secreted, then functioning as a potent mitogenic growth factor. It is expressed on most mature, conventional B cells (but not on peritoneal CD5+ B cells), and can also be found on the surface of T cells, macrophages, platelets and EBV transformed B lymphoblasts. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic Lymphocytic leukemia. CD23 is expressed by B cells in the follicular mantle zone but not by proliferating germinal centre cells. CD23 is also expressed by eosinophils. CD23 is distinct from the high affinity IgE receptors found on basophils and mast cells, which mediate allergic reactions. The low affinity receptors are thought to play a role in isotype specific immunoregulation. The regulation of CD23 surface expression appears to be integral with the complex IgE system, which involves interactions of cells, cytokines, antibodies and regulatory factors.
Product Type:	Antibodies Primary - Optibodies Antibody
Antibody Type:	monoclonal
Format:	TRIS with 0.03% sodium azide, pH7.2, Concentrate
Storage Temp:	+4 degrees C
Species Reactivity:	human
Applications:	IHC
Data Sheet:	PLEASE CLICK HERE TO DOWNLOAD
Additional Info:	Anti-CD23, mouse monoclonal - Optibodies
Clone number:	BS20
Application Details:	Suitable for IHC-P, IHC-Fr
Control Tissues :	Appendix, tonsil
Host:	Mouse
Uniprot ID:	P06734
Images:	https://nordicbiosite.com/uploaded/images/product_e281ed70-8344-11e7-8cb3-4f3d7e7847e1_01.jpg
Research Area:	Histopathology

Optibodies - Nordic BioSite

BSH-3004-1

1 ml

£548.00

Please sign in or sign up to order this product online.

Product Detail:	The human leukocyte differentiation antigen CD23 (FCER2) is a key molecule for B-cell activation and growth. It is the low-affinity receptor for IgE. The truncated molecule can be secreted, then functioning as a potent mitogenic growth factor. It is expressed on most mature, conventional B cells (but not on peritoneal CD5+ B cells), and can also be found on the surface of T cells, macrophages, platelets and EBV transformed B lymphoblasts. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic Lymphocytic leukemia. CD23 is expressed by B cells in the follicular mantle zone but not by proliferating germinal centre cells. CD23 is also expressed by eosinophils. CD23 is distinct from the high affinity IgE receptors found on basophils and mast cells, which mediate allergic reactions. The low affinity receptors are thought to play a role in isotype specific immunoregulation. The regulation of CD23 surface expression appears to be integral with the complex IgE system, which involves interactions of cells, cytokines, antibodies and regulatory factors.
Product Type:	Antibodies Primary - Optibodies Antibody
Antibody Type:	monoclonal
Format:	TRIS with 0.03% sodium azide, pH7.2, Concentrate
Storage Temp:	+4 degrees C
Species Reactivity:	human
Applications:	IHC
Data Sheet:	PLEASE CLICK HERE TO DOWNLOAD
Additional Info:	Anti-CD23, mouse monoclonal - Optibodies
Clone number:	BS20
Application Details:	Suitable for IHC-P, IHC-Fr
Control Tissues :	Appendix, tonsil
Host:	Mouse
Uniprot ID:	P06734
Images:	https://nordicbiosite.com/uploaded/images/product_e225eac0-8344-11e7-8cb3-4f3d7e7847e1_01.jpg
Research Area:	Histopathology

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