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Product Search Results: cd2ap
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Product Search Results: cd2ap

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Product - please click for more details Brand Cat No Size Price (£)

Nordic BioSite AFC-OGPPVD-100 100 tests £454.00
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Product Detail: CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.
Product Type: Antibodies Primary
Antibody Type: monoclonal
Storage Temp: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Immunogen: Normal human blood lymphocytes.
Applications: FC
Additional Info: The antibody LT2 reacts with an extracellular epitope of CD2, a 50 kDa glycoprotein present on the human peripheral blood T lymphocytes and NK cells; also expressed by all thymocytes.
Clone number: LT2
Antibody Isotype: IgG2b
Application Details: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 ?l reagent / 100 ?l of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
Biosite Brand: BioSite Flow
Conjugation: APC
Species Reactivity: human
EntrezGene ID: 914
UniProt No: P06729