Newmarket Scientific
Newmarket Scientific








GenomeMe


Mouse and Rabbit monoclonal antibodies for clinical diagnostic immunohistochemistry


GenomeMe specialises in Mouse and Rabbit monoclonal antibodies for diagnostic IHC (immunohistochemistry). GenomeMe's GeneAb™ antibodies are developed and manufactured in-house, providing full control over their production and quality control leading to truly consitent antibodies for diagnostic use.

 

Use the search to find your antibody. Some antibodies are highlighted below.

 

GenomeMeCE- IVD Antibodies from the GenomeMe range

 



 

PR Antibody Staining

 

PR GeneAb™ Antibody (Cat No: IHC751)

Progesterone Receptor (PR), also known as NR3C3 (Nuclear Receptor Subfamily 3, Group C, Member 3), is an intracellular steroid receptor which mediates the physiological effects of progesterone, a female sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis. Progesterone receptor expression has been linked to the prediction of prognosis in breast cancer, as well as associated responses to endocrine therapy. The progesterone receptor has also been linked to an increased risk for ovarian cancer.

 

PR Antibody (IHC751) Ranked Optimal by NordiQC

 


 

MSH6 Antibody Staining

 

MSH6 GeneAb™ Antibody (Cat No: IHC026)

MutS Homolog 6 (MSH6) is a protein involved in the mismatch repair pathway. This protein is commonly associated with hereditary non-polyposis colorectal cancer, and mutations in this gene are correlated with the development of sporadic colorectal carcinoma. Studies have shown that mutations in MSH6, when co-indicated with mutations in MSH1 and MSH2, contribute to the development of sporadic colorectal carcinoma. Use of Anti-MSH2 is optimized when paired with MSH6, MLH1, and PMS2 in an IHC panel.

 

MSH6 Antibody (IHC026) Ranked Optimal by NordiQC

 


 

HER2 Staining Image

 

HER2/Neu GeneAb™ Antibody (Cat No: IHC042)

The HER2/neu (c-erbB-2) proto-oncogene is a transmembrane receptor tyrosine kinase that is clinically indicated in a number of carcinomas. Overexpression of the c-erbB-2 protein has been associated with ductal breast cancer, as well as pulmonary and gastric adenocarcinomas. A correlation between HER2 and p53 has also been documented, as overexpression of both proteins has been associated with early invasion and metastasis in bladder cancer.

 

HER2/Neu Antibody (IHC042) Ranked Optimal by NordiQC

 


 

CD15 Staining Image

 

CD15 GeneAb™ Antibody (Cat No: IHC527)

Cluster of Differentiation 15 (CD15), also known as Leu-M1, is a carbohydrate adhesion molecule. Positive staining for CD15 and negative staining for leukocyte common antigen or other B- or T-cell lineage markers helps recognise Reed Sternberg cells (RSC) in classic Hodgkin's lymphoma, and distinguishes it from Hodgkin-like neoplasms. CD15 does not stain mesotheliomas and is therefore most useful for distinguishing epithelial mesothelioma from adenocarcinoma.

 

CD15 Antibody (IHC527) Ranked Optimal by NordiQC

 


 

CD56 Staining Image

 

CD56 GeneAb™ Antibody (Cat No: IHC066)

Cluster of Differentiation 56 (CD56), also known as Neural-Cell Adhesion Molecule (NCAM), is a glycoprotein involved in synaptic plasticity, cell-cell adhesion, neurite outgrowth, learning, and memory. NCAM is expressed in normal neurons, glia, natural killer cells, activated T-cells, brain and cerebellum, neuroendocrine tissues, and skeletal muscle. Anti-CD56 recognizes a number of tumours including myeloma, myeloid leukemia, natural killer/T-cell lymphomas, neuroendocrine tumours, pancreatic acinar-cell carcinoma, pheochromocytoma, and Wilm's tumour. CD56 is detectable in neoplasms that are neuroectodermally-derived, such as retinoblastoma, medulloblastomas, astrocytomas, small cell carcinomas, and neuroblastomas. It has also been linked to rhabdomyosarcoma, a tumour that is mesodermally-derived.