Newmarket Scientific
Newmarket Scientific

Histopathology and Immunohistochemistry

Antibodies, stains and detection kits for histopathology and immunohistochemistry (IHC)

GenomeMe.jpg  ImmunoStar logo Monosan logo  

Optibodies logo   zeta-corporation logo



Newmarket Scientific provides reagents used in Histopathology and Immunohistochemistry including: AntibodiesBuffersDetection kitsPAP pensStains and more!


We have a lot of products so please use the search facility above to find what you are looking for or simply email us at


Optibodies logo UKCA Antibodies from the Nordic Biosite Optibodies range


CE- IVD Antibodies from the Nordic Biosite Optibodies range


You may have been using antibodies in Immunohistochemistry for some time and maybe you are getting good results, but Optibodies from Nordic Biosite are on another level.


In producing the Optibodies range Nordic Biosite ensure that every antibody provides beautifully optimised staining. This is the key aim of the Optibodies range and any antibody that does not perform to this standard simply does not make it in to the range.


Optibody™ optimisation involves a great number of tests in order to find the optimal staining conditions...  read more


GenomeMe UKCA Antibodies from the GenomeMe GeneAb™ range

 CE- IVD Antibodies from the GenomeMe GeneAb™ range 


GenomeMe specialises in Mouse and Rabbit monoclonal antibodies for diagnostic IHC (immunohistochemistry). GenomeMe's GeneAb™ antibodies are developed and manufactured in-house, providing full control over their production and quality control leading to truly consitent antibodies for diagnostic use.


Use the search to find your antibody. Some antibodies are highlighted below.


GenomeMe UKCA Antibodies from the Zeta Corporation range

 CE-IVD Antibodies from the Zeta Corporation range 


Zeta Corporation provides the highest quality of IVD antibodies for Pathology/IHC. Zeta antibodies are carefully curated to produce reproducible results on formalin-fixed, paraffin-embedded (FFPE) sections manually or using commercially available automated equipment.


Zeta designs and develops tumor-specific biomarkers using cutting-edge technology to uniquely select the immunogens for the RAbMono™ (Rabbit Monoclonal) and MonoMAb™ (Monospecific monoclonal antibodies).


Zeta utilises its collective knowledge of over 75 years to validate and standardise every antibody individually for immunohistochemistry (IHC). 


Use the search to find your antibody. Some antibodies are highlighted below.


GenomeMe Highlighted Antibodies


PR Antibody Staining


PR GeneAb™ Antibody (Cat No: IHC751)

Progesterone Receptor (PR), also known as NR3C3 (Nuclear Receptor Subfamily 3, Group C, Member 3), is an intracellular steroid receptor which mediates the physiological effects of progesterone, a female sex hormone involved in the menstrual cycle, pregnancy, and embryogenesis. Progesterone receptor expression has been linked to the prediction of prognosis in breast cancer, as well as associated responses to endocrine therapy. The progesterone receptor has also been linked to an increased risk for ovarian cancer.


PR Antibody (IHC751) Ranked Optimal by NordiQC



MSH6 Antibody Staining


MSH6 GeneAb™ Antibody (Cat No: IHC026)

MutS Homolog 6 (MSH6) is a protein involved in the mismatch repair pathway. This protein is commonly associated with hereditary non-polyposis colorectal cancer, and mutations in this gene are correlated with the development of sporadic colorectal carcinoma. Studies have shown that mutations in MSH6, when co-indicated with mutations in MSH1 and MSH2, contribute to the development of sporadic colorectal carcinoma. Use of Anti-MSH2 is optimized when paired with MSH6, MLH1, and PMS2 in an IHC panel.


MSH6 Antibody (IHC026) Ranked Optimal by NordiQC



HER2 Staining Image


HER2/Neu GeneAb™ Antibody (Cat No: IHC042)

The HER2/neu (c-erbB-2) proto-oncogene is a transmembrane receptor tyrosine kinase that is clinically indicated in a number of carcinomas. Overexpression of the c-erbB-2 protein has been associated with ductal breast cancer, as well as pulmonary and gastric adenocarcinomas. A correlation between HER2 and p53 has also been documented, as overexpression of both proteins has been associated with early invasion and metastasis in bladder cancer.


HER2/Neu Antibody (IHC042) Ranked Optimal by NordiQC



CD15 Staining Image


CD15 GeneAb™ Antibody (Cat No: IHC527)

Cluster of Differentiation 15 (CD15), also known as Leu-M1, is a carbohydrate adhesion molecule. Positive staining for CD15 and negative staining for leukocyte common antigen or other B- or T-cell lineage markers helps recognise Reed Sternberg cells (RSC) in classic Hodgkin's lymphoma, and distinguishes it from Hodgkin-like neoplasms. CD15 does not stain mesotheliomas and is therefore most useful for distinguishing epithelial mesothelioma from adenocarcinoma.


CD15 Antibody (IHC527) Ranked Optimal by NordiQC



CD56 Staining Image


CD56 GeneAb™ Antibody (Cat No: IHC066)

Cluster of Differentiation 56 (CD56), also known as Neural-Cell Adhesion Molecule (NCAM), is a glycoprotein involved in synaptic plasticity, cell-cell adhesion, neurite outgrowth, learning, and memory. NCAM is expressed in normal neurons, glia, natural killer cells, activated T-cells, brain and cerebellum, neuroendocrine tissues, and skeletal muscle. Anti-CD56 recognizes a number of tumours including myeloma, myeloid leukemia, natural killer/T-cell lymphomas, neuroendocrine tumours, pancreatic acinar-cell carcinoma, pheochromocytoma, and Wilm's tumour. CD56 is detectable in neoplasms that are neuroectodermally-derived, such as retinoblastoma, medulloblastomas, astrocytomas, small cell carcinomas, and neuroblastomas. It has also been linked to rhabdomyosarcoma, a tumour that is mesodermally-derived.


Zeta Corp Highlighted Antibodies


MUC-4 Antibody Staining



Rabbit Monoclonal Antibody

Clone: ZR201 (Cat No: Z2520)


The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play essential roles in protecting the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. MUC-4 transcripts have been detected in normal respiratory epithelium and lung. MUC-4 is a specific (100%) and sensitive (90%) marker of lung adenocarcinomas and is negative for mesotheliomas. Reportedly, MUC-4 expression in invasive ductal carcinoma of the pancreas is an independent factor for poor prognosis. MUC-4 is also explicitly expressed in low-grade fibromyxoid sarcoma and sclerosing fibrosarcoma.


Anti-MUC-4 Antibody - Rabbit Monoclonal DataSheet



TFE3 Antibody Staining


Transcription factor E3 Antibody (TFE3)

Rabbit Monoclonal Antibody

Clone: ZR365 (Cat No: Z2605)


Transcription factor E3 (TFE3) belongs to the basic helix-loop-helix zipper transcription factor family. The TFE3 gene is located on the short arm of the X chromosome, is expressed in various cells of the human body, and participates in the regulation of various genes. The rearrangement of this gene is associated with a variety of tumors, and it is highly expressed in acinar soft tissue sarcoma with TFE3 fusion gene, Xp11.2 translocation/TFE3 gene fusion-related renal cell carcinoma, and in perivascular epithelioid cell tumors.


Anti-TFE3 Antibody - Rabbit Monoclonal DataSheet



LEF1 Antibody Staining


Lymphoid Enhancing Factor 1 Antibody (LEF1)

Rabbit Monoclonal Antibody

Clone: ZR336 (Cat No: Z2642)


Lymphoid Enhancing Factor 1 (LEF1) is a transcription factor that belongs to the TCF/LEF family. LEF1 participates as a regulator in Wnt signaling pathways. LEF1 is an important factor in lymphopoiesis and is expressed normally in T and pro-B cells but not expressed in mature B cells. Strong nuclear expression of LEF1 has been observed in majority of chronic lymphocytic leukemia/small lymphocytic lymphoma cases and LEF1 is not detected in other small B cell lymphomas. Anti-LEF1 may be used as an aid for differentiation of chronic lymphocytic leukemia/small lymphocytic lymphoma from other small B cell lymphomas.


Anti-LEF1 Antibody - Rabbit Monoclonal DataSheet



Ultra Sensitive Immunohistochemistry


Monosan Plus AP Polymer kits are highly sensitive detection kits intended for use in immunohistochemistry (IHC). They can be used in combination with monoclonal and polyclonal primary antibodies from mouse, rabbit, rat, and guinea pig for the detection of antigens in fixed paraffin-embedded tissue sections, frozen tissue sections and cytological samples.


The kits use an enzyme polymer, carrying multiple secondary antibodies, covalently bound to multiple alkaline phosphatase (AP) molecules. An enzyme-substrate reaction then provides the beautifully clear staining.


These kits are low cost and very high quality, making them the perfect kit for all IHC staining - manual or automated.


For more information email us at



NS Reagents - Antibodies for Neuroscience


The Newmarket Scientific NS reagents range was launched 3 years ago and now contains more than 100 antibodies with many more in development.


We aim to support the forefront of neuroscience research, continually reviewing the latest publications to identify new and re-emerging neuroscience targets that need new and better antibodies. We have a specific focus on neurodegenerative diseases but cover neuroscience more generally too and we will be adding new focus areas as the range develops further.


Need an antibody to a new protein... Why not get in early while we are very actively developing the range?


View the full NS reagents antibody range.