Newmarket Scientific
Newmarket Scientific








MONOSAN


Antibodies for cancer research and multi drug resistance (MDR)


MONOSAN antibodies are developed both by MONOSAN laboratories in house and in collaboration with universities and research institutes throughout Europe, ensuring that all MONOSAN antibodies are extensively tested.

 

Monosan has a focus on antibodies and reagents for cancer research, however they cover many areas so please use the search above to find antibodies to your specific target protein, using either the catalogue number or antigen name or email tech@nktscientific.com.

 

 



Monosan Antibodies for Cancer Research

 

CK 7 Staining

Mouse anti Keratin 7, clone OVTL12/30 

 

This antibody specifically binds Keratin 7, staining a 54 kD band of cytoskeletal proteins in immunobloting. It binds both human and mouse Keratin 7 and is also a useful histopathology marker for distinguishing between ovarian carcinomas and colon carcinomas in FFPE tissue sections.


Read about other MONOSAN antibodies for cancer research.

 



Breast Cancer Drug Resistance Antibodies 

 

Tumour cell insensitivity to anticancer drugs frequently appears as multidrug resistance (MDR), associated with the overexpression of one or more of a set of at least 10 different molecules, causing reduced drug levels at the intracellular target sites.

 

These overexpressed molecules include transmembrane transporter proteins such as P glycoprotein, MRP1-9 and BCRP. In addition, the lung-resistance protein, recently identified as the major vault protein, has also been associated with MDR.


Our Monosan monoclonal antibodies specifically recognise these proteins and so can be used to help identify their roles in clinical drug resistance and explore their occurrence in normal human tissues and physiology. 

 

Here we highlight 4 of our Multi Drug Resistance Antibodies and list all of the available antibodies.

 

BXP21_VUMC 1_200_200x

 



Ultra Sensitive Immunohistochemistry
Monosan%20polymer%20ihc%20detection%20kits

 

Monosan Plus AP Polymer kits are highly sensitive detection kits intended for use in immunohistochemistry (IHC). They can be used in combination with monoclonal and polyclonal primary antibodies from mouse, rabbit, rat, and guinea pig for the detection of antigens in fixed paraffin-embedded tissue sections, frozen tissue sections and cytological samples.

 

The kits use an enzyme polymer, carrying multiple secondary antibodies, covalently bound to multiple alkaline phosphatase (AP) molecules. An enzyme-substrate reaction then provides the beautifully clear staining.

 

These kits are low cost and very high quality, making them the perfect kit for all IHC staining - manual or automated.

 

For more information email us at tech@nktscientific.com.

 



The Newmarket Scientific Antibody Guarantee
Ns antibody guarantee

At Newmarket Scientific we work hard to ensure we only supply the highest quality antibodies and reagents. That's why we are happy to offer you a 100% guarantee for every antibody or antibody reagent you purchase from us.

 

This means that we guarantee our antibody or reagent will work for all the applications stated on the datasheet. So if you buy an antibody from us (including our partner ranges) and it does not work for your application when the datasheet says that it will, we will give you your money back*.

 

So why not give us a try. It's risk free!

 

Use the search above to find the antibody you need or alternatively email us at tech@nktscientific.com and we'll search for you.

 

* Naturally you need to show us that an antibody has not worked, but this guarantee is not just words, we really do mean it, so please ask us for details if you are not sure.