Newmarket Scientific
Newmarket Scientific

Highlighted Antibody - SOX10 - Transcription factor SOX-10 (Clone BS7)

SOX10 is important and sensitive marker of melanoma especially for spindle cell and desmoplastic melanomas and schwannian neoplasms.


This antibody provides truly optimal staining and as with all our antibodies we provide a 100% guarantee, so trying it really is risk free.


Suggested Protocol after paraffin removal and rehydration:


1. Pretreatment: HIER pH9

2. Wash (TBS-Tween)

3. Primary antibody: SOX10 1:100 – 1:400, 30 min.

4. Wash

5. 3% H2O2, 10 min 

6. Wash

7. HRP One-Step Polymer, 30 min

8. Wash

9. Wash

10. DAB high contrast Kit, 10 min

11. Aqua

12. CuSO4 -post enhancement, 5 min

13. Aqua

14. Counter staining in diluted Mayer, 1 min

15. Bluing, 7 min in tap water

16. Dehydration, clearing and mounting


Optibodies™ are mouse and rabbit monoclonal antibodies that have been developed specifically for use in immunohistochemistry to have high affinity and high specificity to their target antigens, give a high signal to noise ratio and can be used to achieve an intensive and specific staining.


Anti-SOX10 (Clone BS7)  Anti-SOX10 datasheet.jpg


Please visit our optibodies page and follow the individual product links for more information about the full optibodies range.



Optimal results for Optibodies™ in External QC assessments!


In recent quality assessments by External QC service providers, optimal staining results were obtained for SEVEN different Optibodies clones:

SOX10 - Transcription factor SOX-10 (Clone BS7)

CK5 - Cytokeratin 5 (Clone BSR55)

HER2 - IHC (Clone BSR44)

EpCAM - Epithelial cell-cell adhesion molecule (Clone BS14)

SMA - Alpha-Smooth Muscle Actin (Clone BS66)

MLA - Melan A (Clone BS52)

PDL-1 - Programmed Death Ligand 1 (Clone BSR90)


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