Newmarket Scientific
Newmarket Scientific








NS Reagents PLCG2 Antibody



PLCG2 Antibody (Cat No: AB21-10139)

 

Phospholipase C-gamma2 (PLCG2) is an enzyme mainly expressed in immune cells (including microglia) which are involved in innate immunity. It is involved in the transmembrane transduction of immune signals that determine the fate and function of various immune cell types.

 

PLCG2 has higher expression levels in pathologically affected brain regions in Alzheimer’s disease indicating that the immune system may play a key role in the development of Alzheimer’s disease and a polymorphism in phospholipase C-gamma 2 (PLCG2) has been reported to be protective against late onset Alzheimer’s disease (LOAD) [1].

 

PRICE: 50ug - £220  or  100ug - £275

 

Please contact us for your free sample (tech@nktscientific.com).

 


 PLCG2 antibody (AB21-10139) 1-100 in IF of Raw 264.7 Cells

 

  PLCG2 Antibody (Cat No: AB21-10139)

 

  Cells: Raw 264.7 Cells

 

  Technique: IF

 

  Primary Ab dilution: 1:200

 PLCG2 antibody (AB21-10139) 1-200 in IHC of Rat Brain

 

  PLCG2 Antibody (Cat No: AB21-10139)

 

  Tissue: Mouse Heart

 

  Technique: IHC

 

  Primary Ab dilution: 1:200

 


 

References:

 

[1] Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J et al (2017) Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immu nity in Alzheimer’s disease. Nat Genet 49:1373– 1384.

 


 


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