Newmarket Scientific Product Search Results for anti-MATR3

Product Search Results: anti-MATR3
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Product Search Results: anti-MATR3	Num Products Matched: 2	2

Newmarket Scientific - NS Reagents

AB19-10089-100ug

100 µg

£275.00

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Product Detail:	Anti-MATR3/Matrin3 Antibody (Polyclonal)
Background Info:	Matrin 3 (MATR3) is a DNA and RNA binding protein with a range of functions in nucleic acid metabolism including gene transcription, splicing, RNA degradation and the DNA damage response. Mutations of the MATR3 gene are associated with distal myopathy, vocal cord and pharyngeal weakness, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). However even without the presence of MATR3 mutations, patients with ALS due to C9orf72 hexanucleotide expansions and FUS mutations may also have cytoplasmic Matrin 3 accumulation as well as strong nuclear Matrin 3 immunostaining indicating that Matrin 3 may more generally be a common mediator in ALS.
Product Type:	NS Reagents Antibody
Antibody Type:	Polyclonal
Format:	100 µg in 100 µl PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
Storage Temp:	6 months: 4°C. Long-term storage: -20°C. Avoid multiple freeze and thaw cycles.
Host Animal:	Rabbit
Species Reactivity:	Human, Mouse
Expected Species:	If you would like us to check if this antibody is likely to bind to this protein from a different species please contact us. We are happy to check for you.
Immunogen:	Full length recombinant human MATR3
Applications:	WB
Data Sheet:	PLEASE CLICK HERE TO DOWNLOAD
Additional Info:	If you would like further information regarding the immunogen used in the production of this antibody or have a query about whether this antibody will bind to your protein/species please contact us and we can do the analysis for you.
Antibody Isotype:	IgG
Application Details:	WB 1:500-2000.
Category:	Primary Antibodies
Other names:	MPD2, ALS21, VCPDM, Matrin-3, Vocal Cord And Pharyngeal Weakness With Distal Myopathy, Myopathy Distal 2, KIAA0723
Research Areas:	Neuroscience
NS Reagents Product Area:	Neuroscience
Peptide Sequence (Internal Use only):	? Full Protein is 847 aa in length
Molecular Weight:	95kDa (Intended as a general guide and does not allow for all isoforms and species variations)
Subcellular location:	Nucleus
Purification:	Affinity purification
Uniprot ID:	P43243
Gene ID:	9782
Gene symbol:	MATR3
Release Date:	May 2019

Newmarket Scientific - NS Reagents

AB19-10089-50ug

50 µg

£220.00

Please sign in or sign up to order this product online.

Product Detail:	Anti-MATR3/Matrin3 Antibody (Polyclonal)
Background Info:	Matrin 3 (MATR3) is a DNA and RNA binding protein with a range of functions in nucleic acid metabolism including gene transcription, splicing, RNA degradation and the DNA damage response. Mutations of the MATR3 gene are associated with distal myopathy, vocal cord and pharyngeal weakness, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). However even without the presence of MATR3 mutations, patients with ALS due to C9orf72 hexanucleotide expansions and FUS mutations may also have cytoplasmic Matrin 3 accumulation as well as strong nuclear Matrin 3 immunostaining indicating that Matrin 3 may more generally be a common mediator in ALS.
Product Type:	NS Reagents Antibody
Antibody Type:	Polyclonal
Format:	50 µg in 50 µl PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
Storage Temp:	6 months: 4°C. Long-term storage: -20°C. Avoid multiple freeze and thaw cycles.
Host Animal:	Rabbit
Species Reactivity:	Human, Mouse
Expected Species:	If you would like us to check if this antibody is likely to bind to this protein from a different species please contact us. We are happy to check for you.
Immunogen:	Full length recombinant human MATR3
Applications:	WB
Data Sheet:	PLEASE CLICK HERE TO DOWNLOAD
Additional Info:	If you would like further information regarding the immunogen used in the production of this antibody or have a query about whether this antibody will bind to your protein/species please contact us and we can do the analysis for you.
Antibody Isotype:	IgG
Application Details:	WB 1:500-2000.
Category:	Primary Antibodies
Other names:	MPD2, ALS21, VCPDM, Matrin-3, Vocal Cord And Pharyngeal Weakness With Distal Myopathy, Myopathy Distal 2, KIAA0723
Research Areas:	Neuroscience
NS Reagents Product Area:	Neuroscience
Peptide Sequence (Internal Use only):	? Full Protein is 847 aa in length
Molecular Weight:	95kDa (Intended as a general guide and does not allow for all isoforms and species variations)
Subcellular location:	Nucleus
Purification:	Affinity purification
Uniprot ID:	P43243
Gene ID:	9782
Gene symbol:	MATR3
Release Date:	May 2019

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Product Search Results: anti-MATR3

Product Search Results: anti-MATR3

Anti-Matrin 3 Antibody

Anti-Matrin 3 Antibody