Newmarket Scientific Product Search Results for amyloglo

Product Search Results: amyloglo
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Product Search Results: amyloglo	Num Products Matched: 2	2

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Biosensis

TR-400-AG

1 kit (5 mL)

£359.00

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Product Detail:	The Biosensis AG-400-AG kit utilizes an ethidium bromide counter stain for a quick and effective way to visualize cell nuclei and cell bodies of cells while under UV illumination allowing the assessment of amyloid plaques and cell/tissue positioning as well in one step.Amylo-Glo® RTDReady to Dilute Staining reagent is designed to stain amyloid plaques in tissue sections. This novel marker has several advantages over other conventional markers such as Thioflavin S and Congo Red because of its unique chemical and spectral properties. (L. Schmued et al. (2012) J.Neuroscience Methods 209:120 126). Using Amylo-Glo® results in a very bright blue UV excitable stain under physiological conditions that will not bleed through when illuminated with other filters. Its brightness makes it ideal for low magnification quantification studies, while its unique excitation/emission profile and mild staining conditions makes it ideal for combination for multiple immunofluorescent labeling studies. Amylo-Glo® RTDis compatible with fresh, frozen, and formalin-fixed immunohistochemistry or cytochemistry, and it is particularly good for confocal and multiple labeling because of its high fluorescent intensity and high resistance to photo-bleaching. Moreover because Amylo-Glo® fluoresces in the UV channel, double and triple labeling experiments can be performed very easily (see protocol).
Product Type:	Tracing/Staining Kit
Format:	The reagents in the Amyloid Plaque Stain Reagent (100x) are all supplied in a liquid format and are ready-to-dilute.
Storage Temp:	The stock solution can be stored for up to 6 months at 4 °C protected from light. No preservatives. Use sterile technique when handling and proper laboratory procedures.
Species Reactivity:	Human, Mouse, Rat, other species expected
Applications:	IH, Frozen; IH(P), Paraffin; IC;
Data Sheet:	PLEASE CLICK HERE TO DOWNLOAD
Application Details:	Staining of amyloid plaques in human and animal tissues, see included protocol. EtBr counter stain stains nuclei and cell bodies for easy identification and spacial orientation.
Alternative Names:	AmyloGlo
Kit Components:	1 bottle containing 40 mL of 10X Amylo-Glo® RTD (A-G RTD) solution 1 bottle containing 40 mL of 10X A-G RTD Ethidium Bromide (EtBr RTD) solution
Reconstitution:	Ready to dilute per protocol 10X solutions
Shelf Life:	6 months from date of purchase
Specificity:	amyloid plaques both intraneuronal and vascular for A-G, Etbr, nuclei and cell bodies both DNA and RNA label \|
Related Products:	Amyloid beta research\| TR-300-AG, MOAB-2 antibody
Purity:	Thin layer chromatography using alumina plates and a solvent system of ethanol and water (3:1) revealed the presence of two fluorescent isomers. No amount of starting material was detected.

Biosensis

TR-300-AG

1 kit (5 mL)

£301.00

Please sign in or sign up to order this product online.

Product Detail:	Amylo-Glo® RTDReady to Dilute Staining reagent is designed to stain amyloid plaques in tissue sections. This novel marker has several advantages over other conventional markers such as Thioflavin S and Congo Red because of its unique chemical and spectral properties. (L. Schmued et al. (2012) J.Neuroscience Methods 209:120 126). Using Amylo-Glo® results in a very bright blue UV excitable stain under physiological conditions that will not bleed through when illuminated with other filters. Its brightness makes it ideal for low magnification quantification studies, while its unique excitation/emission profile and mild staining conditions makes it ideal for combination for multiple immunofluorescent labeling studies. Amylo-Glo® RTDis compatible with fresh, frozen, and formalin-fixed immunohistochemistry or cytochemistry, and it is particularly good for confocal and multiple labeling because of its high fluorescent intensity and high resistance to photo-bleaching. Moreover because Amylo-Glo® fluoresces in the UV channel, double and triple labeling experiments can be performed very easily (see protocol).
Product Type:	Tracing/Staining Kit
Format:	The reagents in the Amyloid Plaque Stain Reagent (100x) are all supplied in a liquid format and are ready-to-dilute.
Storage Temp:	The stock solution can be stored for up to 6 months after date of receipt at 4 °C protected from light. No preservatives. Use sterile technique when handling and proper laboratory procedures.
Species Reactivity:	Human, Mouse, Rat, other species expected
Applications:	IH, Frozen; IH(P), Paraffin; IC;
Data Sheet:	PLEASE CLICK HERE TO DOWNLOAD
Application Details:	Staining of amyloid plaques in human and animal tissues, see included protocol
Alternative Names:	AmyloGlo
Kit Components:	5 mL of 100X Amylo-Glo RTD (A-G RTD) solution
Reconstitution:	Ready to dilute per protocol; 100X
Shelf Life:	6 months from date of purchase
Specificity:	amyloid plaques both intraneuronal and vascular \|
References:	Palombo F (2017) "Detection of A? plaque-associated astrogliosis in Alzheimer's disease brain by spectroscopic imaging and immunohistochemistry."Analyst. [Epub ahead of print] 2017; Application: IF Species: MouseAbud EM (2017) "Generation of Human Microglia from Induced Pluripotent Stem Cells to Study Innate Immunity in Neurological Diseases."PhD Thesis. 2017; Application: IF Species: MouseAbud EM et al. (2017) "iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases."Neuron. 2017; 49(2):278-93 Application: IF Species: MouseSolomon IH et al. (2017) "Brain and liver pathology, amyloid deposition, and interferon responses among older HIV-positive patients in the late HAART era."BMC Infect Dis. 2017; 17(1):151 Application: IF Species: HumanXu F et al. (2016) "Cerebral vascular amyloid seeds drive amyloid ?-protein fibril assembly with a distinct anti-parallel structure."Nat Commun. 2016; 7:13527. Application: IF Species: MouseKatsouri L et al. (2016) "PPARγ-coactivator-1α gene transfer reduces neuronal loss and amyloid-? generation by reducing ?-secretase in an Alzheimer's disease model ."Proc Natl Acad Sci USA. 2016; 113(43):12292-97. Application: IF Species: MouseEsposito G et al. (2016) "Autologous transplantation of intestine-isolated glia cells improves neuropathology and restores cognitive deficits in ? amyloid-induced neurodegeneration."Sci Rep. 2016; 6: 22605. Application: IF Species: RatMarsh SE et al. (2016) "The adaptive immune system restrains Alzheimer's disease pathogenesis by modulating microglial function."Proc Natl Sci USA. Feb 16. pii: 201525466. Application: IF Species: Hu Fibrillar amyloid visualization.Kim YH et al. (2015) "A 3D human neural cell culture system for modeling Alzheimer's disease."Nat Protoc. Jul;10(7):985-1006. Application: IF Species: Hu, Human neural stem-cell-derived three-dimensional (3D) culture system.Nijholt DA et al. (2015) "Pregnancy Zone Protein is Increased in the Alzheimer's Disease Brain and Associates with Senile Plaques."J Alzheimer's Disease. 46(1):227-38. Application: IF Species: HuKamphuis W et al. (2015) "GFAP and vimentin deficiency alters gene expression in astrocytes and microglia in wild-type mice and changes the transcriptional response of reactive glia in mouse model for Alzheimer's disease."Glia. Jun;63(6):1036-56. Application: IF Species: MouseChoi SH et al. (2014) "A three-dimensional human neural cell culture model of Alzheimer's disease."Nature Oct 12. doi: 10.1038/nature1380. Application: IF Species: Hu, Human neural stem-cell-derived three-dimensional (3D) culture system.Niedowicz DM et al. (2014). "Obesity and diabetes cause cognitive dysfunction in the absence of accelerated beta-amyloid deposition in a novel murine model of mixed or vascular dementia." Acta Neuropathol Commun. 2014 Jun 10;2:64.
Related Products:	Amyloid beta research \| Amylo-Glo / EB kit catalog number TR-400-AG
Purity:	Thin layer chromatography using alumina plates and a solvent system of ethanol and water (3:1) revealed the presence of two fluorescent isomers. No amount of starting material was detected.

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