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Product Search Results: AS10 708-25
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Product Search Results: AS10 708-25

 Num Products Matched: 1 1

Product - please click for more details Brand Cat No Size Price (£)

Agrisera AS10 708-25 25 µg £235.00
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Background Info: Oxidative derivate of guanosine is called 8-Hydroxyguanosine (8OHdG) and is used as a popular biomarker of oxidative stress.
Product Type: Antibody
Antibody Type: Monoclonal
Format: Liquid
Storage Temp: Store lyophilized/reconstituted at -20 °C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
Host Animal: Mouse
Species Reactivity: Recognizes markers of oxidative damage to DNA (8-hydroxy-2’-deoxyguanosine, 8-hydroxyguanine and 8-hydroxyguanosine)
Immunogen: 8-hydroxy-guanosine-BSA and – casein conjugates
Applications: ELISA (ELISA), Immunoaffinity chromatography (IAP), Immunohistochemistry on frozen tissue and paraffin-embedded (IHC-Fr-P)
Data Sheet: PLEASE CLICK HERE TO DOWNLOAD
Additional Info: Protocol for immunostaining using this antibody can be found here.
Application Details: The optimal working dilution should be determined by the investigator
Conjugation: IgG2A
Isotype: IgG2A
Purity: Total IgG fraction. Protein G purified.
Not reactive in: No confirmed exceptions from predicted reactivity are currently known
Selected references: Poborilova et al. (2015). DNA hypomethylation concomitant with the overproduction of ROS induced by naphthoquinone juglone on tobacco BY-2 suspension cells. Environmental and Experimental Botany, Volume 113, May 2015, Pages 28–39.Haigh and Drew (2015). Cavitation during the protein misfolding cyclic amplification (PMCA) method - The trigger for de novo prion generation? Biochem Biophys Res Commun. 2015 Apr 17. pii: S0006-291X(15)00726-3. doi: 10.1016/j.bbrc.2015.04.048.
Special application note: Protein G purified IgG2B in PBS, pH 7,4 with 0,09 % sodium azide and 50 % glycerol at concentration 0,65 mg/ml
Research area: Cancer