Product Search Results : SIH-255

Num PRODUCTS MATCHED : 2

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StressMarq

SIH-255-100MG

100 mg

£23.00

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Product Detail:	HDAC inhibitor
Background Info:	Sodium phenylbutyrate is metabolized in the human body by beta-oxidation to phenylacetate, which is then conjugated with glutamine to phenylacetylglutamine, which is eliminated with urine (1). It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of fetal hemoglobin through transcriptional activation of gamma-globin gene (2).
Product Type:	Small Molecules
Storage Temp:	-20ºC
Research Area(s):	Cancer \| Apoptosis \| Cancer Growth Inhibitors \| HDAC Inhibitors
Alternative Name(s):	Sodium 4-phenylbutanoate, 4-PB
Category:	Inducer
References:	1. Batashaw M.L., MacArthur R.B., and Tuchman M. (2001) J Pediatr. 138: S46-54. 2. Melichar B., et al. (1998) Clin Cancer Res. 4:3069-3076.
Country of Origin:	Canada
CAS No.:	1716-12-7
MolecularFormula:	C10H11NaO2
Molecular Weight:	186.18
Source:	Synthetic
Purity:	>98%
Solubility:	Soluble to 1100 mM in water and 100 mM in DMSO
Appearance:	White solid
Safety Phrases:	Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

StressMarq

SIH-255-500MG

500 mg

£52.00

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Product Detail:	HDAC inhibitor
Background Info:	Sodium phenylbutyrate is metabolized in the human body by beta-oxidation to phenylacetate, which is then conjugated with glutamine to phenylacetylglutamine, which is eliminated with urine (1). It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of fetal hemoglobin through transcriptional activation of gamma-globin gene (2).
Product Type:	Small Molecules
Storage Temp:	-20ºC
Research Area(s):	Cancer \| Apoptosis \| Cancer Growth Inhibitors \| HDAC Inhibitors
Alternative Name(s):	Sodium 4-phenylbutanoate, 4-PB
Category:	Inducer
References:	1. Batashaw M.L., MacArthur R.B., and Tuchman M. (2001) J Pediatr. 138: S46-54. 2. Melichar B., et al. (1998) Clin Cancer Res. 4:3069-3076.
Country of Origin:	Canada
CAS No.:	1716-12-7
MolecularFormula:	C10H11NaO2
Molecular Weight:	186.18
Source:	Synthetic
Purity:	>98%
Solubility:	Soluble to 1100 mM in water and 100 mM in DMSO
Appearance:	White solid
Safety Phrases:	Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

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